Differentiating Transition Zone Cancers From Benign Prostatic Hyperplasia by Histogram Analysis of Apparent Diffusion Coefficient Maps With Standard and Ultrahigh b-value Diffusion-weighted MR Imaging.
J Comput Assist Tomogr
; 43(2): 235-241, 2019.
Article
en En
| MEDLINE
| ID: mdl-30475249
ABSTRACT
OBJECTIVE:
To compare the diagnostic performance of standard and ultrahigh b-value Diffusion-weighted Imaging (DWI) using volumetric histogram analysis in differentiating transition zone (TZ) cancer from benign prostatic hyperplasia (BPH).METHODS:
57 TZ cancer and 61 BPH patients received standard (1000 s/mm) and ultrahigh b-value (2000 s/mm) DWI. The diagnostic ability of ADC histogram parameters derived from two DWI for differentiating TZ cancer from BPH was determined by receiver operating characteristic curve.RESULTS:
Median, minimum, the 10th, 25th percentile ADC in both ADC1000 and ADC2000 and skewness in ADC2000 had significant differences between TZ cancer and BPH (for all, P < 0.05).The 10th percentile ADC showed highest area under the ROC curve (AUC) in both ADC1000 and ADC2000.The 10th percentile ADC of ADC2000 showed significantly higher AUC than did ADC1000 (P = 0.0385).CONCLUSIONS:
The 10th percentile ADC obtained from ultrahigh b-value DWI performed better for differentiating TZ cancer from BPH.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Hiperplasia Prostática
/
Neoplasias de la Próstata
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Procesamiento de Imagen Asistido por Computador
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Imagen de Difusión por Resonancia Magnética
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Aged
/
Aged80
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
J Comput Assist Tomogr
Año:
2019
Tipo del documento:
Article