Cyclohexanone curcumin analogs inhibit the progression of castration-resistant prostate cancer in vitro and in vivo.

Mapoung, Sariya; Suzuki, Shugo; Fuji, Satoshi; Naiki-Ito, Aya; Kato, Hiroyuki; Yodkeeree, Supachai; Ovatlarnporn, Chitchamai; Takahashi, Satoru; Limtrakul Dejkriengkraikul, Pornngarm

Cyclohexanone curcumin analogs inhibit the progression of castration-resistant prostate cancer in vitro and in vivo.

Mapoung, Sariya; Suzuki, Shugo; Fuji, Satoshi; Naiki-Ito, Aya; Kato, Hiroyuki; Yodkeeree, Supachai; Ovatlarnporn, Chitchamai; Takahashi, Satoru; Limtrakul Dejkriengkraikul, Pornngarm.

Afiliación

Mapoung S; Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Suzuki S; Center for Research and Development of Natural Products for Health, Chiang Mai University, Chiang Mai, Thailand.
Fuji S; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Naiki-Ito A; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Kato H; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Yodkeeree S; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Ovatlarnporn C; Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Takahashi S; Center for Research and Development of Natural Products for Health, Chiang Mai University, Chiang Mai, Thailand.
Limtrakul Dejkriengkraikul P; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla, Thailand.

Cancer Sci ; 110(2): 596-607, 2019 Feb.

Article en En | MEDLINE | ID: mdl-30499149

Asunto(s)

Curcumina/farmacología; Ciclohexanonas/farmacología; Neoplasias de la Próstata Resistentes a la Castración/tratamiento farmacológico; Animales; Apoptosis/efectos de los fármacos; Ciclo Celular/efectos de los fármacos; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Progresión de la Enfermedad; Resistencia a Antineoplásicos/efectos de los fármacos; Humanos; Masculino; Metaloproteinasa 2 de la Matriz/metabolismo; Metaloproteinasa 9 de la Matriz/metabolismo; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Recurrencia Local de Neoplasia/tratamiento farmacológico; Recurrencia Local de Neoplasia/metabolismo; Células PC-3; Neoplasias de la Próstata Resistentes a la Castración/metabolismo; Ensayos Antitumor por Modelo de Xenoinjerto/métodos

Palabras clave

anti-cancer; anti-metastasis; curcumin analog; pharmacokinetics; prostate cancer

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Curcumina / Ciclohexanonas / Neoplasias de la Próstata Resistentes a la Castración Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cancer Sci Año: 2019 Tipo del documento: Article País de afiliación: Tailandia

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