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The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance.
Nardone, Agostina; Weir, Hazel; Delpuech, Oona; Brown, Henry; De Angelis, Carmine; Cataldo, Maria Letizia; Fu, Xiaoyong; Shea, Martin J; Mitchell, Tamika; Veeraraghavan, Jamunarani; Nagi, Chandandeep; Pilling, Mark; Rimawi, Mothaffar F; Trivedi, Meghana; Hilsenbeck, Susan G; Chamness, Gary C; Jeselsohn, Rinath; Osborne, C Kent; Schiff, Rachel.
Afiliación
  • Nardone A; Lester & Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Weir H; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02210, USA.
  • Delpuech O; Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Brown H; Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • De Angelis C; Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Cataldo ML; Lester & Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Fu X; Lester & Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Shea MJ; Lester & Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Mitchell T; Lester & Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Veeraraghavan J; Lester & Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Nagi C; Lester & Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Pilling M; Lester & Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Rimawi MF; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Trivedi M; Quantitative Biology, Discovery Science, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Hilsenbeck SG; Department of Medicine, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Chamness GC; Lester & Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Jeselsohn R; Department of Medicine, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Osborne CK; Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, TX, USA.
  • Schiff R; Lester & Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Br J Cancer ; 120(3): 331-339, 2019 02.
Article en En | MEDLINE | ID: mdl-30555156

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptores de Estrógenos / Cinamatos / Indoles / Neoplasias Hormono-Dependientes Límite: Animals / Female / Humans Idioma: En Revista: Br J Cancer Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptores de Estrógenos / Cinamatos / Indoles / Neoplasias Hormono-Dependientes Límite: Animals / Female / Humans Idioma: En Revista: Br J Cancer Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos