Hitting Undruggable Targets: Viewing Stabilized Peptide Development through the Lens of Quantitative Systems Pharmacology.

Atangcho, Lydia; Navaratna, Tejas; Thurber, Greg M

Atangcho, Lydia; Navaratna, Tejas; Thurber, Greg M.

Afiliación

Atangcho L; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.
Navaratna T; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.
Thurber GM; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA. Electronic address: gthurber@umich.edu.

Trends Biochem Sci ; 44(3): 241-257, 2019 03.

Article en En | MEDLINE | ID: mdl-30563724

Asunto(s)

Péptidos Cíclicos/química; Péptidos/química; Animales; Diseño de Fármacos; Humanos

Palabras clave

alpha helices; cyclic peptides; lipophilicity; macrocycles; pharmacokinetics; stabilized peptides

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Péptidos / Péptidos Cíclicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Trends Biochem Sci Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google