Perverted Downward Corrective Saccades During Horizontal Head Impulses in Chiari Malformation.
Cerebellum
; 18(3): 333-339, 2019 Jun.
Article
en En
| MEDLINE
| ID: mdl-30610539
ABSTRACT
The mechanism of perverted vertical responses during horizontal head impulse tests (HITs) requires further elucidation. A 47-year-old woman with a Chiari malformation showed alternating skew deviation, downbeat nystagmus with an increasing slow phase velocity, impaired smooth pursuit, and upward ocular deviation during horizontal HITs and corrective downward saccades in the presence of normal bithermal caloric tests and intact tilt suppressions of the post-rotatory nystagmus. These findings suggest dysfunction of the inferior cerebellum including the tonsil, nodulus, and uvula. We propose that disruption of signals from the medial part of the vestibulocerebellum, which normally inhibits the lateral and anterior canal pathways, may elicit an upward misdirection of the eye velocity during rapid horizontal head rotation. Otherwise, the Chiari malformation may have directly affected the brainstem structures involved in the direction matrix of the vestibulo-ocular reflex.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Malformación de Arnold-Chiari
/
Movimientos Sacádicos
Tipo de estudio:
Etiology_studies
Límite:
Female
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Humans
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Middle aged
Idioma:
En
Revista:
Cerebellum
Asunto de la revista:
CEREBRO
Año:
2019
Tipo del documento:
Article
País de afiliación:
Corea del Sur