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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
Karlsson Linnér, Richard; Biroli, Pietro; Kong, Edward; Meddens, S Fleur W; Wedow, Robbee; Fontana, Mark Alan; Lebreton, Maël; Tino, Stephen P; Abdellaoui, Abdel; Hammerschlag, Anke R; Nivard, Michel G; Okbay, Aysu; Rietveld, Cornelius A; Timshel, Pascal N; Trzaskowski, Maciej; Vlaming, Ronald de; Zünd, Christian L; Bao, Yanchun; Buzdugan, Laura; Caplin, Ann H; Chen, Chia-Yen; Eibich, Peter; Fontanillas, Pierre; Gonzalez, Juan R; Joshi, Peter K; Karhunen, Ville; Kleinman, Aaron; Levin, Remy Z; Lill, Christina M; Meddens, Gerardus A; Muntané, Gerard; Sanchez-Roige, Sandra; Rooij, Frank J van; Taskesen, Erdogan; Wu, Yang; Zhang, Futao; Auton, Adam; Boardman, Jason D; Clark, David W; Conlin, Andrew; Dolan, Conor C; Fischbacher, Urs; Groenen, Patrick J F; Harris, Kathleen Mullan; Hasler, Gregor; Hofman, Albert; Ikram, Mohammad A; Jain, Sonia; Karlsson, Robert; Kessler, Ronald C.
Afiliación
  • Karlsson Linnér R; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, the Netherlands. r.karlssonlinner@vu.nl.
  • Biroli P; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands. r.karlssonlinner@vu.nl.
  • Kong E; Department of Economics, VU University Amsterdam, Amsterdam, the Netherlands. r.karlssonlinner@vu.nl.
  • Meddens SFW; Department of Economics, University of Zurich, Zurich, Switzerland.
  • Wedow R; Department of Economics, Harvard University, Cambridge, MA, USA.
  • Fontana MA; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, the Netherlands.
  • Lebreton M; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.
  • Tino SP; Department of Economics, VU University Amsterdam, Amsterdam, the Netherlands.
  • Abdellaoui A; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Hammerschlag AR; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Nivard MG; Analytic Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Okbay A; Department of Sociology, Harvard University, Cambridge, MA, USA.
  • Rietveld CA; Center for the Advancement of Value in Musculoskeletal Care, Hospital for Special Surgery, New York, NY, USA.
  • Timshel PN; Department of Healthcare Policy and Research, Weill Cornell Medical College, Cornell University, New York, NY, USA.
  • Trzaskowski M; Amsterdam School of Economics, University of Amsterdam, Amsterdam, the Netherlands.
  • Vlaming R; Amsterdam Brain and Cognition, University of Amsterdam, Amsterdam, the Netherlands.
  • Zünd CL; Department of Economics, University of Toronto, Toronto, Ontario, Canada.
  • Bao Y; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Buzdugan L; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, the Netherlands.
  • Caplin AH; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Chen CY; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, the Netherlands.
  • Eibich P; Department of Economics, VU University Amsterdam, Amsterdam, the Netherlands.
  • Fontanillas P; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.
  • Gonzalez JR; Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.
  • Joshi PK; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Karhunen V; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
  • Kleinman A; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Levin RZ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia.
  • Lill CM; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, the Netherlands.
  • Meddens GA; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.
  • Muntané G; Department of Economics, VU University Amsterdam, Amsterdam, the Netherlands.
  • Sanchez-Roige S; Department of Economics, University of Zurich, Zurich, Switzerland.
  • Rooij FJV; Institute for Social and Economic Research, University of Essex, Colchester, UK.
  • Taskesen E; Seminar for Statistics, Department of Mathematics, ETH Zurich, Zurich, Switzerland.
  • Wu Y; Department of Economics, University of Zurich, Zurich, Switzerland.
  • Zhang F; Stuyvesant High School, New York, NY, USA.
  • Auton A; Socio-Economic Panel Study, DIW Berlin, Berlin, Germany.
  • Boardman JD; Max Planck Institute for Demographic Research, Rostock, Germany.
  • Clark DW; Research, 23andMe, Inc., Mountain View, CA, USA.
  • Conlin A; Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain.
  • Dolan CC; Universitat Pompeu Fabra (UPF), Barcelona, Spain.
  • Fischbacher U; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
  • Groenen PJF; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
  • Harris KM; Center for Life Course Health Research, University of Oulu, Oulu, Finland.
  • Hasler G; Research, 23andMe, Inc., Mountain View, CA, USA.
  • Hofman A; Department of Economics, University of California San Diego, La Jolla, CA, USA.
  • Ikram MA; Genetic and Molecular Epidemiology Group, Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics & Cardiogenetics, University of Lübeck, Lübeck, Germany.
  • Jain S; Team Loyalty BV, Hoofddorp, the Netherlands.
  • Karlsson R; Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.
  • Kessler RC; Research Department, Hospital Universitari Institut Pere Mata, Institut d'Investigació Sanitària Pere Virgili (IISPV), Reus, Spain.
Nat Genet ; 51(2): 245-257, 2019 02.
Article en En | MEDLINE | ID: mdl-30643258
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Conducta / Predisposición Genética a la Enfermedad / Sitios Genéticos Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Límite: Female / Humans / Male Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Conducta / Predisposición Genética a la Enfermedad / Sitios Genéticos Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Límite: Female / Humans / Male Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos