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Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma.
Cheung, Laurene S; Fu, Juan; Kumar, Pankaj; Kumar, Amit; Urbanowski, Michael E; Ihms, Elizabeth A; Parveen, Sadiya; Bullen, C Korin; Patrick, Garrett J; Harrison, Robert; Murphy, John R; Pardoll, Drew M; Bishai, William R.
Afiliación
  • Cheung LS; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231.
  • Fu J; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21231.
  • Kumar P; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231.
  • Kumar A; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231.
  • Urbanowski ME; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231.
  • Ihms EA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231.
  • Parveen S; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231.
  • Bullen CK; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231.
  • Patrick GJ; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231.
  • Harrison R; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231.
  • Murphy JR; Department of Psychology, Northeastern University, Boston, MA 02115.
  • Pardoll DM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231; john.murphy@jhmi.edu dpardol1@jhmi.edu wbishai1@jhmi.edu.
  • Bishai WR; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21231; john.murphy@jhmi.edu dpardol1@jhmi.edu wbishai1@jhmi.edu.
Proc Natl Acad Sci U S A ; 116(8): 3100-3105, 2019 02 19.
Article en En | MEDLINE | ID: mdl-30718426

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Melanoma Experimental / Interleucina-2 / Toxina Diftérica / Receptor de Muerte Celular Programada 1 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Melanoma Experimental / Interleucina-2 / Toxina Diftérica / Receptor de Muerte Celular Programada 1 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article