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Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome.
Di Domenico, Fabio; Tramutola, Antonella; Barone, Eugenio; Lanzillotta, Chiara; Defever, Olivia; Arena, Andrea; Zuliani, Ilaria; Foppoli, Cesira; Iavarone, Federica; Vincenzoni, Federica; Castagnola, Massimo; Butterfield, D Allan; Perluigi, Marzia.
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  • Di Domenico F; Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.
  • Tramutola A; Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.
  • Barone E; Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy; Universidad Autònoma de Chile, Instituto de Ciencias Biomédicas, Facultad de alud, Providencia, Santiago, Chile.
  • Lanzillotta C; Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.
  • Defever O; Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.
  • Arena A; Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.
  • Zuliani I; Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.
  • Foppoli C; CNR Institute of Molecular Biology and Pathology, Sapienza University of Rome, Rome, Italy.
  • Iavarone F; Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, Rome, Italy; Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
  • Vincenzoni F; Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, Rome, Italy; Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
  • Castagnola M; Laboratorio di Proteomica e Metabonomica, IRCCS, Fondazione Santa Lucia - Rome and Istituto per la Chimica del Riconoscimento Molecolare, CNR, Rome, Italy.
  • Butterfield DA; Department of Chemistry and Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.
  • Perluigi M; Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy. Electronic address: marzia.perluigi@uniroma1.it.
Redox Biol ; 23: 101162, 2019 05.
Article en En | MEDLINE | ID: mdl-30876754
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transducción de Señal / Síndrome de Down / Estrés Oxidativo / Sirolimus / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Redox Biol Año: 2019 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transducción de Señal / Síndrome de Down / Estrés Oxidativo / Sirolimus / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Redox Biol Año: 2019 Tipo del documento: Article País de afiliación: Italia