Comparative RNAi Screens in Isogenic Human Stem Cells Reveal SMARCA4 as a Differential Regulator.

Günes, Ceren; Paszkowski-Rogacz, Maciej; Rahmig, Susann; Khattak, Shahryar; Camgöz, Aylin; Wermke, Martin; Dahl, Andreas; Bornhäuser, Martin; Waskow, Claudia; Buchholz, Frank

Günes, Ceren; Paszkowski-Rogacz, Maciej; Rahmig, Susann; Khattak, Shahryar; Camgöz, Aylin; Wermke, Martin; Dahl, Andreas; Bornhäuser, Martin; Waskow, Claudia; Buchholz, Frank.

Afiliación

Günes C; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany.
Paszkowski-Rogacz M; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany.
Rahmig S; Regeneration in Hematopoiesis, Leibniz Institute on Aging - Fritz Lipmann Institute, 07745 Jena, Germany.
Khattak S; Stem Cell Engineering Facility, Biotechnology Center, TU Dresden, 01307 Dresden, Germany.
Camgöz A; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany.
Wermke M; Department of Medicine I, University Hospital Carl Gustav Carus, 01307 Dresden, Germany; Medical Faculty and University Hospital Carl Gustav Carus, Early Clinical Trial Unit, 01307 Dresden, Germany.
Dahl A; Dresden Genome Center (DGC), TU Dresden, 01307 Dresden, Germany.
Bornhäuser M; Department of Medicine I, University Hospital Carl Gustav Carus, 01307 Dresden, Germany.
Waskow C; Regeneration in Hematopoiesis, Leibniz Institute on Aging - Fritz Lipmann Institute, 07745 Jena, Germany; Department of Medicine III, Faculty of Medicine, Fetscherstrasse 74, 01307 Dresden, Germany.
Buchholz F; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany; German Cancer Research Center (DKFZ), Heidelberg and German Research Consortium (DKTK), Partner Site Dresden, 01307 Dresden, Germany; National Center for Tumor Diseases

Stem Cell Reports ; 12(5): 1084-1098, 2019 05 14.

Article en En | MEDLINE | ID: mdl-31031192

Asunto(s)

ADN Helicasas/genética; Ensayos Analíticos de Alto Rendimiento/métodos; Células Madre Pluripotentes Inducidas/metabolismo; Células-Madre Neurales/metabolismo; Proteínas Nucleares/genética; Interferencia de ARN; Factores de Transcripción/genética; Animales; Diferenciación Celular/genética; Autorrenovación de las Células/genética; Células Cultivadas; Células Madre Hematopoyéticas/citología; Células Madre Hematopoyéticas/metabolismo; Humanos; Células Madre Pluripotentes Inducidas/citología; Ratones; Células-Madre Neurales/citología; Trasplante de Células Madre/métodos; Células Madre/citología; Células Madre/metabolismo

Palabras clave

RNAi; SMARCA4; SWI/SNF; comparative functional profiling; hematopoiesis; isogenic; neural differentiation; self-renewal

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas Nucleares / ADN Helicasas / Interferencia de ARN / Células Madre Pluripotentes Inducidas / Ensayos Analíticos de Alto Rendimiento / Células-Madre Neurales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Stem Cell Reports Año: 2019 Tipo del documento: Article País de afiliación: Alemania

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