Serotype b of <i>Aggregatibacter actinomycetemcomitans</i> triggers pro-inflammatory responses and amyloid beta secretion in hippocampal cells: a novel link between periodontitis and Alzheimer´s disease?

Díaz-Zúñiga, J; Muñoz, Y; Melgar-Rodríguez, S; More, J; Bruna, B; Lobos, P; Monasterio, G; Vernal, R; Paula-Lima, A

Serotype b of Aggregatibacter actinomycetemcomitans triggers pro-inflammatory responses and amyloid beta secretion in hippocampal cells: a novel link between periodontitis and Alzheimer´s disease?

Díaz-Zúñiga, J; Muñoz, Y; Melgar-Rodríguez, S; More, J; Bruna, B; Lobos, P; Monasterio, G; Vernal, R; Paula-Lima, A.

Afiliación

Díaz-Zúñiga J; Department of Conservative Dentistry, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Muñoz Y; Biomedical Neuroscience Institute, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Melgar-Rodríguez S; Aging Cellular Laboratory, Faculty of Sciences, Universidad de Chile, Santiago, Chile.
More J; Department of Conservative Dentistry, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Bruna B; Biomedical Neuroscience Institute, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Lobos P; Biomedical Neuroscience Institute, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Monasterio G; Biomedical Neuroscience Institute, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Vernal R; Department of Conservative Dentistry, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Paula-Lima A; Department of Conservative Dentistry, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.

J Oral Microbiol ; 11(1): 1586423, 2019.

Article en En | MEDLINE | ID: mdl-31044031

Palabras clave

Alzheimer´s disease; Periodontitis; cytokines; inflammation; microglia; neurons

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: J Oral Microbiol Año: 2019 Tipo del documento: Article País de afiliación: Chile