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Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.
Zhao, Yue; Zhao, Chenxi; Lu, Jin; Wu, Jun; Li, Changhao; Hu, Zhiye; Tian, Wei; Yang, Liang; Xiang, Jin; Zhou, Haibin; Deng, Zixin; Huang, Jian; Hong, Kui.
Afiliación
  • Zhao Y; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, PR China.
  • Zhao C; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei Province, 430072, PR China.
  • Lu J; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, PR China.
  • Wu J; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei Province, 430072, PR China.
  • Li C; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei Province, 430072, PR China.
  • Hu Z; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, PR China.
  • Tian W; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, PR China.
  • Yang L; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, PR China.
  • Xiang J; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, PR China.
  • Zhou H; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, PR China.
  • Deng Z; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, PR China.
  • Huang J; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei Province, 430072, PR China. Electronic address: jianhuang@whu.edu.cn.
  • Hong K; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, PR China. Electronic address: kuihong31@whu.edu.cn.
Pharmacol Res ; 146: 104294, 2019 08.
Article en En | MEDLINE | ID: mdl-31175940
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptor alfa de Estrógeno / Sesterterpenos Límite: Female / Humans Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptor alfa de Estrógeno / Sesterterpenos Límite: Female / Humans Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article