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Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria: Structure-activity relationships and mode of action studies.
Masci, Domiziana; Hind, Charlotte; Islam, Mohammad K; Toscani, Anita; Clifford, Melanie; Coluccia, Antonio; Conforti, Irene; Touitou, Meir; Memdouh, Siham; Wei, Xumin; La Regina, Giuseppe; Silvestri, Romano; Sutton, J Mark; Castagnolo, Daniele.
Afiliación
  • Masci D; School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9NH, United Kingdom; Department of Drug Chemistry and Technologies, Sapienza University of Rome, Laboratory Affiliated to Instituto Pasteur Italia - Fondazione Cenci Bolognetti, Piazzale Aldo Moro 5, I-00185, Roma, Ital
  • Hind C; Research and Development Institute, National Infections Service, Public Health England, Porton Down, Salisbury, SP4 0JG, Wiltshire, United Kingdom.
  • Islam MK; School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9NH, United Kingdom.
  • Toscani A; School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9NH, United Kingdom.
  • Clifford M; Research and Development Institute, National Infections Service, Public Health England, Porton Down, Salisbury, SP4 0JG, Wiltshire, United Kingdom.
  • Coluccia A; Department of Drug Chemistry and Technologies, Sapienza University of Rome, Laboratory Affiliated to Instituto Pasteur Italia - Fondazione Cenci Bolognetti, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
  • Conforti I; School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9NH, United Kingdom; Department of Drug Chemistry and Technologies, Sapienza University of Rome, Laboratory Affiliated to Instituto Pasteur Italia - Fondazione Cenci Bolognetti, Piazzale Aldo Moro 5, I-00185, Roma, Ital
  • Touitou M; School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9NH, United Kingdom.
  • Memdouh S; School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9NH, United Kingdom.
  • Wei X; School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9NH, United Kingdom.
  • La Regina G; Department of Drug Chemistry and Technologies, Sapienza University of Rome, Laboratory Affiliated to Instituto Pasteur Italia - Fondazione Cenci Bolognetti, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
  • Silvestri R; Department of Drug Chemistry and Technologies, Sapienza University of Rome, Laboratory Affiliated to Instituto Pasteur Italia - Fondazione Cenci Bolognetti, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
  • Sutton JM; Research and Development Institute, National Infections Service, Public Health England, Porton Down, Salisbury, SP4 0JG, Wiltshire, United Kingdom. Electronic address: mark.sutton@phe.gov.uk.
  • Castagnolo D; School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9NH, United Kingdom. Electronic address: daniele.castagnolo@kcl.ac.uk.
Eur J Med Chem ; 178: 500-514, 2019 Sep 15.
Article en En | MEDLINE | ID: mdl-31202995
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirroles / Farmacorresistencia Bacteriana / Bacterias Gramnegativas / Bacterias Grampositivas / Antibacterianos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirroles / Farmacorresistencia Bacteriana / Bacterias Gramnegativas / Bacterias Grampositivas / Antibacterianos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article