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Hyperandrogenism and insulin resistance-induced fetal loss: evidence for placental mitochondrial abnormalities and elevated reactive oxygen species production in pregnant rats that mimic the clinical features of polycystic ovary syndrome.
Zhang, Yuehui; Zhao, Wei; Xu, Hongfei; Hu, Min; Guo, Xiaozhu; Jia, Wenyan; Liu, Guoqi; Li, Juan; Cui, Peng; Lager, Susanne; Sferruzzi-Perri, Amanda Nancy; Li, Wei; Wu, Xiao-Ke; Han, Yanhua; Brännström, Mats; Shao, Linus R; Billig, Håkan.
Afiliación
  • Zhang Y; Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, 150040, Harbin, China.
  • Zhao W; Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, 40530, Gothenburg, Sweden.
  • Xu H; Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, 150040, Harbin, China.
  • Hu M; Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, 150040, Harbin, China.
  • Guo X; Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, 40530, Gothenburg, Sweden.
  • Jia W; Department of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, 510120, Guangzhou, China.
  • Liu G; Institute of Integrated Traditional Chinese Medicine and Western Medicine, Guangzhou Medical University, 510120, Guangzhou, China.
  • Li J; Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, 150040, Harbin, China.
  • Cui P; Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, 150040, Harbin, China.
  • Lager S; Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, 150040, Harbin, China.
  • Sferruzzi-Perri AN; Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, 40530, Gothenburg, Sweden.
  • Li W; Department of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, 510120, Guangzhou, China.
  • Wu XK; Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, 40530, Gothenburg, Sweden.
  • Han Y; Department of Women's and Children's Health, Uppsala University, 75185, Uppsala, Sweden.
  • Brännström M; Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.
  • Shao LR; Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, 150040, Harbin, China.
  • Billig H; Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, 150040, Harbin, China.
J Physiol ; 597(15): 3927-3950, 2019 08.
Article en En | MEDLINE | ID: mdl-31206177
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndrome del Ovario Poliquístico / Trofoblastos / Aborto Espontáneo / Especies Reactivas de Oxígeno / Hiperandrogenismo / Mitocondrias Tipo de estudio: Etiology_studies Límite: Animals / Pregnancy Idioma: En Revista: J Physiol Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndrome del Ovario Poliquístico / Trofoblastos / Aborto Espontáneo / Especies Reactivas de Oxígeno / Hiperandrogenismo / Mitocondrias Tipo de estudio: Etiology_studies Límite: Animals / Pregnancy Idioma: En Revista: J Physiol Año: 2019 Tipo del documento: Article País de afiliación: China