Toxin-antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA-KacT complex.

Qian, Hongliang; Yu, Hao; Li, Peifei; Zhu, E; Yao, Qingqing; Tai, Cui; Deng, Zixin; Gerdes, Kenn; He, Xinyi; Gan, Jianhua; Ou, Hong-Yu

Qian, Hongliang; Yu, Hao; Li, Peifei; Zhu, E; Yao, Qingqing; Tai, Cui; Deng, Zixin; Gerdes, Kenn; He, Xinyi; Gan, Jianhua; Ou, Hong-Yu.

Afiliación

Qian H; State Key Laboratory of Microbial Metabolism, Joint International Laboratory on Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China.
Yu H; State Key Laboratory of Microbial Metabolism, Joint International Laboratory on Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China.
Li P; State Key Laboratory of Microbial Metabolism, Joint International Laboratory on Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China.
Zhu E; State Key Laboratory of Microbial Metabolism, Joint International Laboratory on Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China.
Yao Q; State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai 200438, China.
Tai C; State Key Laboratory of Microbial Metabolism, Joint International Laboratory on Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China.
Deng Z; State Key Laboratory of Microbial Metabolism, Joint International Laboratory on Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China.
Gerdes K; Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen N, Denmark.
He X; State Key Laboratory of Microbial Metabolism, Joint International Laboratory on Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China.
Gan J; State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai 200438, China.
Ou HY; State Key Laboratory of Microbial Metabolism, Joint International Laboratory on Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China.

Nucleic Acids Res ; 47(14): 7690-7702, 2019 08 22.

Article en En | MEDLINE | ID: mdl-31260525

Asunto(s)

Antitoxinas/genética; Proteínas Bacterianas/genética; Toxinas Bacterianas/genética; Klebsiella pneumoniae/genética; Complejos Multiproteicos/genética; Operón; Antitoxinas/química; Antitoxinas/metabolismo; Proteínas Bacterianas/química; Proteínas Bacterianas/metabolismo; Toxinas Bacterianas/química; Toxinas Bacterianas/metabolismo; Cristalografía por Rayos X; Regulación Bacteriana de la Expresión Génica; Klebsiella pneumoniae/metabolismo; Modelos Moleculares; Complejos Multiproteicos/química; Complejos Multiproteicos/metabolismo; Unión Proteica; Conformación Proteica; Multimerización de Proteína

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Operón / Proteínas Bacterianas / Toxinas Bacterianas / Antitoxinas / Complejos Multiproteicos / Klebsiella pneumoniae Idioma: En Revista: Nucleic Acids Res Año: 2019 Tipo del documento: Article País de afiliación: China

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