The first activation study of the ß-carbonic anhydrases from the pathogenic bacteria <i>Brucella suis</i> and <i>Francisella tularensis</i> with amines and amino acids.

Angeli, Andrea; Del Prete, Sonia; Pinteala, Mariana; Maier, Stelian S; Donald, William A; Simionescu, Bogdan C; Capasso, Clemente; Supuran, Claudiu T

The first activation study of the ß-carbonic anhydrases from the pathogenic bacteria Brucella suis and Francisella tularensis with amines and amino acids.

Angeli, Andrea; Del Prete, Sonia; Pinteala, Mariana; Maier, Stelian S; Donald, William A; Simionescu, Bogdan C; Capasso, Clemente; Supuran, Claudiu T.

Afiliación

Angeli A; a Neurofarba Department, Sezione di Scienze Farmaceutiche e Nutraceutiche , Università degli Studi di Firenze , Sesto Fiorentino , Italy.
Del Prete S; b Istituto di Bioscienze e Biorisorse , CNR , Napoli , Italy.
Pinteala M; c Centre of Advanced Research in Bionanoconjugates and Biopolymers Department , "Petru Poni" Institute of Macromolecular Chemistry , Iasi , Romania.
Maier SS; c Centre of Advanced Research in Bionanoconjugates and Biopolymers Department , "Petru Poni" Institute of Macromolecular Chemistry , Iasi , Romania.
Donald WA; d Polymers Research Center, Polymeric Release Systems Research Group , "Gheorghe Asachi" Technical University of Iasi , Iasi , Romania.
Simionescu BC; e School of Chemistry , University of New South Wales , Sydney , Australia.
Capasso C; c Centre of Advanced Research in Bionanoconjugates and Biopolymers Department , "Petru Poni" Institute of Macromolecular Chemistry , Iasi , Romania.
Supuran CT; b Istituto di Bioscienze e Biorisorse , CNR , Napoli , Italy.

J Enzyme Inhib Med Chem ; 34(1): 1178-1185, 2019 Dec.

Article en En | MEDLINE | ID: mdl-31282230

Asunto(s)

Aminas/farmacología; Aminoácidos/farmacología; Brucella suis/enzimología; Anhidrasas Carbónicas/metabolismo; Activación Enzimática/efectos de los fármacos; Francisella tularensis/enzimología; Aminas/química; Aminoácidos/química; Anhidrasas Carbónicas/genética; Relación Estructura-Actividad

Palabras clave

Carbonic anhydrase; activators; bacteria; metalloenzymes

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Anhidrasas Carbónicas / Brucella suis / Activación Enzimática / Francisella tularensis / Aminas / Aminoácidos Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Italia

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