Next generation sequencing identifies baseline viral mutants associated with treatment response to pegylated interferon in HBeAg-positive chronic hepatitis B.

Chuaypen, Natthaya; Payungporn, Sunchai; Poovorawan, Kittiyod; Chotiyaputta, Watcharasak; Piratvisuth, Teerha; Tangkijvanich, Pisit

Chuaypen, Natthaya; Payungporn, Sunchai; Poovorawan, Kittiyod; Chotiyaputta, Watcharasak; Piratvisuth, Teerha; Tangkijvanich, Pisit.

Afiliación

Chuaypen N; Faculty of Medicine, Center of Excellence in Hepatitis and Liver Cancer, Chulalongkorn University, Bangkok, Thailand.
Payungporn S; Faculty of Medicine, Center of Excellence in Hepatitis and Liver Cancer, Chulalongkorn University, Bangkok, Thailand.
Poovorawan K; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Chotiyaputta W; Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Piratvisuth T; NKC Institute of Gastroenterology and Hepatology, Prince of Songkla University, Songkhla, Thailand.
Tangkijvanich P; Department of Biochemistry, Faculty of Medicine, Center of Excellence in Hepatitis and Liver Cancer, Chulalongkorn University, 1873 Rama 4 Road, Pathumwan, Bangkok, 10330, Thailand. Pisit.T@chula.ac.th.

Virus Genes ; 55(5): 610-618, 2019 Oct.

Article en En | MEDLINE | ID: mdl-31359359

Asunto(s)

Antivirales/uso terapéutico; Variación Genética; Virus de la Hepatitis B/genética; Hepatitis B Crónica/tratamiento farmacológico; Hepatitis B Crónica/virología; Interferones/uso terapéutico; Mutación; Adolescente; Adulto; Femenino; Genotipo; Antígenos del Núcleo de la Hepatitis B/genética; Antígenos e de la Hepatitis B/sangre; Virus de la Hepatitis B/aislamiento & purificación; Secuenciación de Nucleótidos de Alto Rendimiento; Humanos; Masculino; Persona de Mediana Edad; Prevalencia; Regiones Promotoras Genéticas; Resultado del Tratamiento; Adulto Joven

Palabras clave

HBV; Mutations; NGS; PEG-IFN; Treatment response

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Antivirales / Variación Genética / Virus de la Hepatitis B / Interferones / Hepatitis B Crónica / Mutación Tipo de estudio: Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Virus Genes Asunto de la revista: BIOLOGIA MOLECULAR / VIROLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Tailandia

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