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The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis.
Singh, Siddharth; Kumar, Manoj; Kumar, Sanjeev; Sen, Shrinka; Upadhyay, Pawan; Bhattacharjee, Sayan; M, Naveen; Tomar, Vivek Singh; Roy, Siddhartha; Dutt, Amit; Kundu, Tapas K.
Afiliación
  • Singh S; Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru 560064, India.
  • Kumar M; Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru 560064, India.
  • Kumar S; BioCOS Life Sciences Pvt. Ltd., Bengaluru, India.
  • Sen S; Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru 560064, India.
  • Upadhyay P; Integrated Cancer Genomics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Center, Navi Mumbai, India.
  • Bhattacharjee S; Department of Structural Biology and Bioinformatics, Indian Institute of Chemical Biology, Kolkata 700032, India.
  • M N; BioCOS Life Sciences Pvt. Ltd., Bengaluru, India.
  • Tomar VS; Department of Microbiology and Cell Biology, Indian Institute of Science, Bengaluru 560012, India.
  • Roy S; Department of Biophysics, Bose Institute, Kolkata 700054, India.
  • Dutt A; Integrated Cancer Genomics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Center, Navi Mumbai, India.
  • Kundu TK; Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru 560064, India tapas@jncasr.ac.in.
J Biol Chem ; 294(38): 14081-14095, 2019 09 20.
Article en En | MEDLINE | ID: mdl-31366730
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Carcinogénesis Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article País de afiliación: India
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Carcinogénesis Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article País de afiliación: India