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Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes.
Musa, Julian; Cidre-Aranaz, Florencia; Aynaud, Marie-Ming; Orth, Martin F; Knott, Maximilian M L; Mirabeau, Olivier; Mazor, Gal; Varon, Mor; Hölting, Tilman L B; Grossetête, Sandrine; Gartlgruber, Moritz; Surdez, Didier; Gerke, Julia S; Ohmura, Shunya; Marchetto, Aruna; Dallmayer, Marlene; Baldauf, Michaela C; Stein, Stefanie; Sannino, Giuseppina; Li, Jing; Romero-Pérez, Laura; Westermann, Frank; Hartmann, Wolfgang; Dirksen, Uta; Gymrek, Melissa; Anderson, Nathaniel D; Shlien, Adam; Rotblat, Barak; Kirchner, Thomas; Delattre, Olivier; Grünewald, Thomas G P.
Afiliación
  • Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Aynaud MM; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France.
  • Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Mirabeau O; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Mazor G; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France.
  • Varon M; Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
  • Hölting TLB; Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
  • Grossetête S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Gartlgruber M; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France.
  • Surdez D; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Gerke JS; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France.
  • Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Westermann F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Hartmann W; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Dirksen U; Division of Translational Pathology, Gerhard-Domagk Institute of Pathology, University Hospital of Münster, Münster, Germany.
  • Gymrek M; Department of Pediatric Hematology and Oncology, University Hospital of Essen, Essen, Germany.
  • Anderson ND; Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Shlien A; Department of Computer Science and Engineering, University of California, San Diego, La Jolla, CA, USA.
  • Rotblat B; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
  • Kirchner T; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
  • Delattre O; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
  • Grünewald TGP; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Nat Commun ; 10(1): 4128, 2019 09 11.
Article en En | MEDLINE | ID: mdl-31511524
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Mutación de Línea Germinal / Neoplasias Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Mutación de Línea Germinal / Neoplasias Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Alemania