ß-Arrestin 2 mediates arginine vasopressin-induced IL-6 induction via the ERK<sub>1/2</sub>-NF-&#954;B signal pathway in murine hearts.

Sun, Shu-Zhen; Cao, Hong; Yao, Na; Zhao, Ling-Ling; Zhu, Xiao-Fang; Ni, Er-An; Zhu, Qi; Zhu, Wei-Zhong

ß-Arrestin 2 mediates arginine vasopressin-induced IL-6 induction via the ERK_1/2-NF-κB signal pathway in murine hearts.

Sun, Shu-Zhen; Cao, Hong; Yao, Na; Zhao, Ling-Ling; Zhu, Xiao-Fang; Ni, Er-An; Zhu, Qi; Zhu, Wei-Zhong.

Afiliación

Sun SZ; Cardiovascular laboratory, Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, China.
Cao H; Cardiovascular laboratory, Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, China.
Yao N; Cardiovascular laboratory, Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, China.
Zhao LL; Cardiovascular laboratory, Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, China.
Zhu XF; Cardiovascular laboratory, Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, China.
Ni EA; Cardiovascular laboratory, Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, China.
Zhu Q; Cardiovascular laboratory, Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, China.
Zhu WZ; Cardiovascular laboratory, Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, 226001, China. Zhuwz@ntu.edu.cn.

Acta Pharmacol Sin ; 41(2): 198-207, 2020 Feb.

Article en En | MEDLINE | ID: mdl-31515529

Asunto(s)

Arginina Vasopresina/farmacología; Corazón/fisiopatología; Interleucina-6/metabolismo; Arrestina beta 2/genética; Animales; Arginina Vasopresina/administración & dosificación; Relación Dosis-Respuesta a Droga; Fibroblastos/metabolismo; Técnicas de Silenciamiento del Gen; Insuficiencia Cardíaca/fisiopatología; Masculino; Ratones; Ratones Noqueados; Proteína Quinasa 1 Activada por Mitógenos/metabolismo; Proteína Quinasa 3 Activada por Mitógenos/metabolismo; FN-kappa B/metabolismo; Ratas; Ratas Sprague-Dawley; Receptores de Vasopresinas/metabolismo

Palabras clave

ERK1/2; IL-6; adult rat cardiac fibroblasts; arginine vasopressin; myocardial inflammation; ß-Arrestin 2

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Arginina Vasopresina / Interleucina-6 / Arrestina beta 2 / Corazón Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China

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