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Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression.
Merola, Jonathan; Reschke, Melanie; Pierce, Richard W; Qin, Lingfeng; Spindler, Susann; Baltazar, Tania; Manes, Thomas D; Lopez-Giraldez, Francesc; Li, Guangxin; Bracaglia, Laura G; Xie, Catherine; Kirkiles-Smith, Nancy; Saltzman, W Mark; Tietjen, Gregory T; Tellides, George; Pober, Jordan S.
Afiliación
  • Merola J; Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.
  • Reschke M; Department of Biomedical Engineering, Yale School of Engineering and Applied Science, New Haven, Connecticut, USA.
  • Pierce RW; Department of Pediatrics, and.
  • Qin L; Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.
  • Spindler S; Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.
  • Baltazar T; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA.
  • Manes TD; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA.
  • Lopez-Giraldez F; Yale Center for Genome Analysis and Department of Genetics, Yale University, New Haven, Connecticut, USA.
  • Li G; Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.
  • Bracaglia LG; Department of Biomedical Engineering, Yale School of Engineering and Applied Science, New Haven, Connecticut, USA.
  • Xie C; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA.
  • Kirkiles-Smith N; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA.
  • Saltzman WM; Department of Biomedical Engineering, Yale School of Engineering and Applied Science, New Haven, Connecticut, USA.
  • Tietjen GT; Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.
  • Tellides G; Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.
  • Pober JS; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA.
JCI Insight ; 4(20)2019 10 17.
Article en En | MEDLINE | ID: mdl-31527312

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Nucleares / Transactivadores / Microglobulina beta-2 / Ingeniería de Tejidos / Células Endoteliales / Aloinjertos / Rechazo de Injerto Tipo de estudio: Prognostic_studies Idioma: En Revista: JCI Insight Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Nucleares / Transactivadores / Microglobulina beta-2 / Ingeniería de Tejidos / Células Endoteliales / Aloinjertos / Rechazo de Injerto Tipo de estudio: Prognostic_studies Idioma: En Revista: JCI Insight Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos