Expression of CEA, CA125, CA19-9 and human milk fat globule membrane antigen in ovarian tumours.
J Clin Pathol
; 41(3): 260-4, 1988 Mar.
Article
en En
| MEDLINE
| ID: mdl-3162916
ABSTRACT
The expression of five different antigens in ovarian tumours was studied by means of an immunohistochemical test with anti-CEA, HMFG1 and HMFG2, NS19-9 and OC125 antibodies. Considerable variation was noted not only between different histological types and between tumours of one type but also between areas in a single tumour. HMFG1 and HMFG2 were the most reactive of all the antibodies; NS19-9 and OC125 were expressed by different populations of cells. It is concluded that specific combinations of antibodies are more effective both for the monitoring of ovarian cancer as well as for immunodiagnosis and treatment, than any single one used.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
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Glicoproteínas de Membrana
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Antígeno Carcinoembrionario
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Biomarcadores de Tumor
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Antígenos de Neoplasias
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Antígenos de Superficie
Límite:
Female
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Humans
Idioma:
En
Revista:
J Clin Pathol
Año:
1988
Tipo del documento:
Article