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A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice.
Hovakimyan, Armine; Antonyan, Tatevik; Shabestari, Sepideh Kiani; Svystun, Olga; Chailyan, Gor; Coburn, Morgan A; Carlen-Jones, William; Petrushina, Irina; Chadarevian, Jean Paul; Zagorski, Karen; Petrovsky, Nikolai; Cribbs, David H; Agadjanyan, Michael G; Ghochikyan, Anahit; Davtyan, Hayk.
Afiliación
  • Hovakimyan A; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA, USA.
  • Antonyan T; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA, USA.
  • Shabestari SK; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA, USA.
  • Svystun O; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA, USA.
  • Chailyan G; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA, USA.
  • Coburn MA; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA, USA.
  • Carlen-Jones W; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.
  • Petrushina I; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA, USA.
  • Chadarevian JP; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
  • Zagorski K; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA, USA.
  • Petrovsky N; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
  • Cribbs DH; Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA, USA.
  • Agadjanyan MG; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, USA.
  • Ghochikyan A; Vaxine Pty Ltd, Flinders Medical Center, Bedford Park, Adelaide, 5042, Australia.
  • Davtyan H; Department of Diabetes and Endocrinology, Faculty of Medicine, Flinders University, Adelaide, 5042, Australia.
Sci Rep ; 9(1): 15455, 2019 10 29.
Article en En | MEDLINE | ID: mdl-31664089

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vacunas / Proteínas tau / Monoéster Fosfórico Hidrolasas / Epítopos Límite: Animals Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vacunas / Proteínas tau / Monoéster Fosfórico Hidrolasas / Epítopos Límite: Animals Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos