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Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
Niska-Blakie, Joanna; Gopinathan, Lakshmi; Low, Kia Ngee; Kien, Yang Lay; Goh, Christine M F; Caldez, Matias J; Pfeiffenberger, Elisabeth; Jones, Oliver S; Ong, Chee Bing; Kurochkin, Igor V; Coppola, Vincenzo; Tessarollo, Lino; Choi, Hyungwon; Kanagasundaram, Yoganathan; Eisenhaber, Frank; Maurer-Stroh, Sebastian; Kaldis, Philipp.
Afiliación
  • Niska-Blakie J; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos #3-09, Singapore, 138673, Republic of Singapore.
  • Gopinathan L; Bioinformatics Institute (BII), A*STAR, Singapore, 138671, Republic of Singapore.
  • Low KN; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos #3-09, Singapore, 138673, Republic of Singapore.
  • Kien YL; Bioinformatics Institute (BII), A*STAR, Singapore, 138671, Republic of Singapore.
  • Goh CMF; Bioinformatics Institute (BII), A*STAR, Singapore, 138671, Republic of Singapore.
  • Caldez MJ; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos #3-09, Singapore, 138673, Republic of Singapore.
  • Pfeiffenberger E; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos #3-09, Singapore, 138673, Republic of Singapore.
  • Jones OS; Department of Biochemistry, National University of Singapore (NUS), Singapore, 117597, Republic of Singapore.
  • Ong CB; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos #3-09, Singapore, 138673, Republic of Singapore.
  • Kurochkin IV; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos #3-09, Singapore, 138673, Republic of Singapore.
  • Coppola V; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos #3-09, Singapore, 138673, Republic of Singapore.
  • Tessarollo L; Bioinformatics Institute (BII), A*STAR, Singapore, 138671, Republic of Singapore.
  • Choi H; Department of Cancer Biology and Genetics, The Ohio State University, 988 Biomedical Research Tower, 460 West 12th Ave, Columbus, OH, 43210, USA.
  • Kanagasundaram Y; Mouse Cancer Genetics Program, National Cancer Institute, NCI-Frederick, Bldg. 560, 1050 Boyles Street, Frederick, MD, 21702-1201, USA.
  • Eisenhaber F; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos #3-09, Singapore, 138673, Republic of Singapore.
  • Maurer-Stroh S; Department of Medicine, National University of Singapore (NUS), Singapore, 117597, Republic of Singapore.
  • Kaldis P; Bioinformatics Institute (BII), A*STAR, Singapore, 138671, Republic of Singapore.
Cell Mol Life Sci ; 77(17): 3423-3439, 2020 Sep.
Article en En | MEDLINE | ID: mdl-31722069
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Envejecimiento / Coenzima A Transferasas / Síndrome Metabólico / Microbioma Gastrointestinal Límite: Animals / Humans Idioma: En Revista: Cell Mol Life Sci Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Envejecimiento / Coenzima A Transferasas / Síndrome Metabólico / Microbioma Gastrointestinal Límite: Animals / Humans Idioma: En Revista: Cell Mol Life Sci Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article