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Structure-Activity Relationship and Crystallographic Studies on 4-Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors.
Holt-Martyn, James P; Chowdhury, Rasheduzzaman; Tumber, Anthony; Yeh, Tzu-Lan; Abboud, Martine I; Lippl, Kerstin; Lohans, Christopher T; Langley, Gareth W; Figg, William; McDonough, Michael A; Pugh, Christopher W; Ratcliffe, Peter J; Schofield, Christopher J.
Afiliación
  • Holt-Martyn JP; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.
  • Chowdhury R; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.
  • Tumber A; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.
  • Yeh TL; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.
  • Abboud MI; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.
  • Lippl K; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.
  • Lohans CT; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.
  • Langley GW; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.
  • Figg W; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.
  • McDonough MA; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.
  • Pugh CW; NDM Research Building, University of Oxford, Oxford, OX3 7FZ, UK.
  • Ratcliffe PJ; NDM Research Building, University of Oxford, Oxford, OX3 7FZ, UK.
  • Schofield CJ; The Francis Crick Institute, London, NW1 1AT, UK.
ChemMedChem ; 15(3): 270-273, 2020 02 05.
Article en En | MEDLINE | ID: mdl-31751494
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirimidinonas / Prolina Dioxigenasas del Factor Inducible por Hipoxia / Inhibidores de Prolil-Hidroxilasa Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: ChemMedChem Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirimidinonas / Prolina Dioxigenasas del Factor Inducible por Hipoxia / Inhibidores de Prolil-Hidroxilasa Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: ChemMedChem Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido