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Apaziquone for Nonmuscle Invasive Bladder Cancer: Where Are We Now?
Arends, Tom J H; Alfred Witjes, Johannes.
Afiliación
  • Arends TJH; Department of Urology, Canisius Wilhelmina Hospital, Weg door Jonkerbos 100, 6532 SZ Nijmegen, The Netherlands.
  • Alfred Witjes J; Department of Urology, Radboud University Nijmegen Medical Centre, Geert Groote plein zuid 10, 6525 GA Nijmegen, The Netherlands. Electronic address: fred.witjes@radboudumc.nl.
Urol Clin North Am ; 47(1): 73-82, 2020 Feb.
Article en En | MEDLINE | ID: mdl-31757302
ABSTRACT
Apaziquone is an interesting drug for intravesical use in patients with nonmuscle invasive bladder cancer; however, more research is needed to prove its actual benefit. Although the apaziquone trials demonstrate the potential of this new drug, the singular phase 3 trials did not reach their primary endpoint. To date, no new trials are recruiting, so the development of apaziquone seems to have stopped.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Aziridinas / Neoplasias de la Vejiga Urinaria / Carcinoma de Células Transicionales / Indolquinonas Límite: Humans Idioma: En Revista: Urol Clin North Am Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Aziridinas / Neoplasias de la Vejiga Urinaria / Carcinoma de Células Transicionales / Indolquinonas Límite: Humans Idioma: En Revista: Urol Clin North Am Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos