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Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.
Santos, Maria C Ferreira Dos; Anderson, Cole P; Neschen, Susanne; Zumbrennen-Bullough, Kimberly B; Romney, Steven J; Kahle-Stephan, Melanie; Rathkolb, Birgit; Gailus-Durner, Valerie; Fuchs, Helmut; Wolf, Eckhard; Rozman, Jan; de Angelis, Martin Hrabe; Cai, Weiling Maggie; Rajan, Malini; Hu, Jennifer; Dedon, Peter C; Leibold, Elizabeth A.
Afiliación
  • Santos MCFD; Department of Medicine, Division of Hematology, University of Utah, Salt Lake City, UT, 84112, USA.
  • Anderson CP; Molecular Medicine Program, University of Utah, Salt Lake City, UT, 84112, USA.
  • Neschen S; Molecular Medicine Program, University of Utah, Salt Lake City, UT, 84112, USA.
  • Zumbrennen-Bullough KB; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, 84112, USA.
  • Romney SJ; Landstuhl Regional Medical Center, 66849, Landstuhl, Germany.
  • Kahle-Stephan M; German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
  • Rathkolb B; German Center for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
  • Gailus-Durner V; Molecular Medicine Program, University of Utah, Salt Lake City, UT, 84112, USA.
  • Fuchs H; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, 84112, USA.
  • Wolf E; Department of Medicine, Division of Hematology, University of Utah, Salt Lake City, UT, 84112, USA.
  • Rozman J; Molecular Medicine Program, University of Utah, Salt Lake City, UT, 84112, USA.
  • de Angelis MH; Thermo Fisher Scientific, Waltham, MA, 02451, USA.
  • Cai WM; German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
  • Rajan M; Medizinische Hochschule Brandenburg Theodor Fontane Institut für Sozialmedizin und Epidemiologie, 14770, Brandenburg an der Havel, Germany.
  • Hu J; German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
  • Dedon PC; German Center for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
  • Leibold EA; Institute of Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-Universität München, Feodor-Lynen Strasse 25, 81377, Munich, Germany.
Nat Commun ; 11(1): 296, 2020 01 15.
Article en En | MEDLINE | ID: mdl-31941883
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: ARNt Metiltransferasas / ARN de Transferencia de Lisina / Proteína 2 Reguladora de Hierro / Insulina / Hierro Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: ARNt Metiltransferasas / ARN de Transferencia de Lisina / Proteína 2 Reguladora de Hierro / Insulina / Hierro Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos