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Targeted therapy guided by single-cell transcriptomic analysis in drug-induced hypersensitivity syndrome: a case report.
Kim, Doyoung; Kobayashi, Tetsuro; Voisin, Benjamin; Jo, Jay-Hyun; Sakamoto, Keiko; Jin, Seon-Pil; Kelly, Michael; Pasieka, Helena B; Naff, Jessica L; Meyerle, Jon H; Ikpeama, Ijeoma D; Fahle, Gary A; Davis, Fred P; Rosenzweig, Sergio D; Alejo, Julie C; Pittaluga, Stefania; Kong, Heidi H; Freeman, Alexandra F; Nagao, Keisuke.
Afiliación
  • Kim D; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), NIH, Bethesda, MD, USA.
  • Kobayashi T; Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Voisin B; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), NIH, Bethesda, MD, USA.
  • Jo JH; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), NIH, Bethesda, MD, USA.
  • Sakamoto K; Cutaneous Microbiome and Inflammation Section, Dermatology Branch, NIAMS, National Institutes of Health (NIH), Bethesda, MD, USA.
  • Jin SP; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), NIH, Bethesda, MD, USA.
  • Kelly M; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), NIH, Bethesda, MD, USA.
  • Pasieka HB; Cancer Research Technology Program, Single-Cell Analysis Facility, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Naff JL; Department of Dermatology, MedStar Washington Hospital Center & Georgetown University Hospital, Washington, DC, USA.
  • Meyerle JH; Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, MD, USA.
  • Ikpeama ID; Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, MD, USA.
  • Fahle GA; Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, MD, USA.
  • Davis FP; Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, MD, USA.
  • Rosenzweig SD; Molecular Immunology and Inflammation Branch, NIAMS, NIH, Bethesda, MD, USA.
  • Alejo JC; Immunology Service, Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, MD, USA.
  • Pittaluga S; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Kong HH; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Freeman AF; Cutaneous Microbiome and Inflammation Section, Dermatology Branch, NIAMS, National Institutes of Health (NIH), Bethesda, MD, USA.
  • Nagao K; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD, USA.
Nat Med ; 26(2): 236-243, 2020 02.
Article en En | MEDLINE | ID: mdl-31959990
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Análisis de la Célula Individual / Transcriptoma / Síndrome de Hipersensibilidad a Medicamentos Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Análisis de la Célula Individual / Transcriptoma / Síndrome de Hipersensibilidad a Medicamentos Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos