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Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models.
Yu, Lu; Zhang, Xiaoli; Yang, Yexin; Li, Dan; Tang, Kaiyuan; Zhao, Zifan; He, Wanwan; Wang, Ce; Sahoo, Nirakar; Converso-Baran, Kimber; Davis, Carol S; Brooks, Susan V; Bigot, Anne; Calvo, Raul; Martinez, Natalia J; Southall, Noel; Hu, Xin; Marugan, Juan; Ferrer, Marc; Xu, Haoxing.
Afiliación
  • Yu L; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 4114 Biological Sciences Building, 1105 North University, Ann Arbor, MI 48109, USA.
  • Zhang X; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 4114 Biological Sciences Building, 1105 North University, Ann Arbor, MI 48109, USA.
  • Yang Y; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 4114 Biological Sciences Building, 1105 North University, Ann Arbor, MI 48109, USA.
  • Li D; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 4114 Biological Sciences Building, 1105 North University, Ann Arbor, MI 48109, USA.
  • Tang K; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China.
  • Zhao Z; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 4114 Biological Sciences Building, 1105 North University, Ann Arbor, MI 48109, USA.
  • He W; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 4114 Biological Sciences Building, 1105 North University, Ann Arbor, MI 48109, USA.
  • Wang C; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 4114 Biological Sciences Building, 1105 North University, Ann Arbor, MI 48109, USA.
  • Sahoo N; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China.
  • Converso-Baran K; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 4114 Biological Sciences Building, 1105 North University, Ann Arbor, MI 48109, USA.
  • Davis CS; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 4114 Biological Sciences Building, 1105 North University, Ann Arbor, MI 48109, USA.
  • Brooks SV; Department of Biology, The University of Texas Rio Grande Valley, 1201 W University Dr., Edinburg, TX 78539, USA.
  • Bigot A; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Calvo R; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Martinez NJ; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Southall N; Sorbonne Université, INSERM, AIM, Center for Research in Myology, UMRS974, GH Pitié-Salpétrière, 75651 Paris Cedex 13, France.
  • Hu X; NIH/NCATS/NCGC, 9800 Medical Center Drive, Rockville, MD 20850, USA.
  • Marugan J; NIH/NCATS/NCGC, 9800 Medical Center Drive, Rockville, MD 20850, USA.
  • Ferrer M; NIH/NCATS/NCGC, 9800 Medical Center Drive, Rockville, MD 20850, USA.
  • Xu H; NIH/NCATS/NCGC, 9800 Medical Center Drive, Rockville, MD 20850, USA.
Sci Adv ; 6(6): eaaz2736, 2020 02.
Article en En | MEDLINE | ID: mdl-32128386
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Distrofia Muscular de Duchenne / Canales de Potencial de Receptor Transitorio / Lisosomas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Adv Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Distrofia Muscular de Duchenne / Canales de Potencial de Receptor Transitorio / Lisosomas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Adv Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos