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DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo.
Leandro, João; Dodatko, Tetyana; Aten, Jan; Nemeria, Natalia S; Zhang, Xu; Jordan, Frank; Hendrickson, Ronald C; Sanchez, Roberto; Yu, Chunli; DeVita, Robert J; Houten, Sander M.
Afiliación
  • Leandro J; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Dodatko T; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Aten J; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Nemeria NS; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Zhang X; Department of Pathology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, 1105 AZ The Netherlands.
  • Jordan F; Department of Chemistry, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA.
  • Hendrickson RC; Department of Chemistry, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA.
  • Sanchez R; Department of Chemistry, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA.
  • Yu C; Microchemistry and Proteomics Core, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • DeVita RJ; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Houten SM; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Hum Mol Genet ; 29(7): 1168-1179, 2020 05 08.
Article en En | MEDLINE | ID: mdl-32160276
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Encefalopatías Metabólicas / Acilcoenzima A / Glutaril-CoA Deshidrogenasa / Errores Innatos del Metabolismo de los Aminoácidos / Complejo Cetoglutarato Deshidrogenasa Límite: Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Encefalopatías Metabólicas / Acilcoenzima A / Glutaril-CoA Deshidrogenasa / Errores Innatos del Metabolismo de los Aminoácidos / Complejo Cetoglutarato Deshidrogenasa Límite: Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos