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Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.
Choi, Insup; Zhang, Yuanxi; Seegobin, Steven P; Pruvost, Mathilde; Wang, Qian; Purtell, Kerry; Zhang, Bin; Yue, Zhenyu.
Afiliación
  • Choi I; Departments of Neurology and Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Zhang Y; Departments of Neurology and Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Seegobin SP; Departments of Neurology and Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Pruvost M; Departments of Neurology and Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Wang Q; Departments of Neurology and Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Purtell K; Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Zhang B; Departments of Neurology and Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Yue Z; Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Nat Commun ; 11(1): 1386, 2020 03 13.
Article en En | MEDLINE | ID: mdl-32170061
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Autofagia / Microglía / Enfermedades Neurodegenerativas / Receptor Toll-Like 4 / Alfa-Sinucleína Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Autofagia / Microglía / Enfermedades Neurodegenerativas / Receptor Toll-Like 4 / Alfa-Sinucleína Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos