Research advances in pericyte function and their roles in diseases.
Chin J Traumatol
; 23(2): 89-95, 2020 Apr.
Article
en En
| MEDLINE
| ID: mdl-32192909
ABSTRACT
Pericyte, a kind of pluripotent cell, may regulate the irrigation flow and permeability of microcirculation. Pericytes are similar to the smooth muscle cells, which express several kinds of contractile proteins and have contractility. The dysfunction of pericytes is related to many microvascular diseases, including hypoxia, hypertension, diabetic retinopathy, fibrosis, inflammation, Alzheimer's disease, multiple sclerosis, and tumor formation. For a long time, their existence and function have been neglected. The distribution, structure, biomarker, related signaling pathways as well as the roles of pericytes on vascular diseases will be introduced in this review.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Investigación
/
Pericitos
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Chin J Traumatol
Asunto de la revista:
TRAUMATOLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
China