Metformin inhibits IL-1ß secretion via impairment of NLRP3 inflammasome in keratinocytes: implications for preventing the development of psoriasis.

Tsuji, Gaku; Hashimoto-Hachiya, Akiko; Yen, Vu Hai; Takemura, Masaki; Yumine, Ayako; Furue, Kazuhisa; Furue, Masutaka; Nakahara, Takeshi

Tsuji, Gaku; Hashimoto-Hachiya, Akiko; Yen, Vu Hai; Takemura, Masaki; Yumine, Ayako; Furue, Kazuhisa; Furue, Masutaka; Nakahara, Takeshi.

Afiliación

Tsuji G; 1Research and Clinical Center for Yusho and Dioxin, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka, 812-8582 Japan.
Hashimoto-Hachiya A; 2Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka, 812-8582 Japan.
Yen VH; 2Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka, 812-8582 Japan.
Takemura M; 2Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka, 812-8582 Japan.
Yumine A; 2Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka, 812-8582 Japan.
Furue K; 1Research and Clinical Center for Yusho and Dioxin, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka, 812-8582 Japan.
Furue M; 2Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka, 812-8582 Japan.
Nakahara T; 1Research and Clinical Center for Yusho and Dioxin, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka, 812-8582 Japan.

Cell Death Discov ; 6: 11, 2020.

Article en En | MEDLINE | ID: mdl-32194991

Palabras clave

Inflammasome; Skin diseases

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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Death Discov Año: 2020 Tipo del documento: Article