mTORC2/Rac1 Pathway Predisposes Cancer Aggressiveness in <i>IDH1-</i>Mutated Glioma.

Liu, Yang; Lu, Yanxin; Li, Aiguo; Celiku, Orieta; Han, Sue; Qian, Mingyu; Yang, Chunzhang

mTORC2/Rac1 Pathway Predisposes Cancer Aggressiveness in IDH1-Mutated Glioma.

Liu, Yang; Lu, Yanxin; Li, Aiguo; Celiku, Orieta; Han, Sue; Qian, Mingyu; Yang, Chunzhang.

Afiliación

Liu Y; Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
Lu Y; Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
Li A; Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
Celiku O; Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
Han S; Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
Qian M; Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
Yang C; Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

Cancers (Basel) ; 12(4)2020 Mar 26.

Article en En | MEDLINE | ID: mdl-32224866

Palabras clave

IDH1 mutation; Rictor; glioma; lamellipodia; mTOR; rac1

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Cancers (Basel) Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos