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1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy.
Kapron, Barbara; Czarnomysy, Robert; Wysokinski, Mariusz; Andrys, Rudolf; Musilek, Kamil; Angeli, Andrea; Supuran, Claudiu T; Plech, Tomasz.
Afiliación
  • Kapron B; Department of Clinical Genetics, I Faculty of Medicine with Dentistry Division, Medical University of Lublin, Lublin, Poland.
  • Czarnomysy R; Department of Synthesis and Technology of Drugs, Faculty of Pharmacy, Medical University of Bialystok, Bialystok, Poland.
  • Wysokinski M; Department of Basic Nursing and Medical Teaching, Chair of Development in Nursing, Faculty of Health Sciences, Medical University of Lublin, Lublin, Poland.
  • Andrys R; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic.
  • Musilek K; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic.
  • Angeli A; Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Firenze, Italy.
  • Supuran CT; Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Firenze, Italy.
  • Plech T; Department of Pharmacology, Faculty of Health Sciences, Medical University of Lublin, Lublin, Poland.
J Enzyme Inhib Med Chem ; 35(1): 993-1002, 2020 Dec.
Article en En | MEDLINE | ID: mdl-32253957
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Triazoles / Inhibidores de Anhidrasa Carbónica / Inhibidores de la Colinesterasa / Epilepsia / Anticonvulsivantes / Antioxidantes Límite: Animals / Humans Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Polonia
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Triazoles / Inhibidores de Anhidrasa Carbónica / Inhibidores de la Colinesterasa / Epilepsia / Anticonvulsivantes / Antioxidantes Límite: Animals / Humans Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Polonia