An ultrafast responsive BODIPY-based fluorescent probe for the detection of endogenous hypochlorite in live cells.
J Mater Chem B
; 5(3): 525-530, 2017 Jan 21.
Article
en En
| MEDLINE
| ID: mdl-32263669
Hypochlorite plays a significant role in various physiological and pathological processes; however, its role is still less clear than the role of other reactive oxygen species. Herein, we report an ultrafast responsive (<0.2 s) and highly selective probe B-Ts for hypochlorite with high sensitivity and a detection limit as low as 7.5 nM. The probe was compatible in a wide pH range of 4-13. More importantly, experiments in live cells showed that the probe could penetrate the cell membrane easily and was capable of imaging endogenous and exogenous hypochlorite specifically with a fast response.
Texto completo:
1
Bases de datos:
MEDLINE
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
J Mater Chem B
Año:
2017
Tipo del documento:
Article