Quantitative proteomic profiling of the rat substantia nigra places glial fibrillary acidic protein at the hub of proteins dysregulated during aging: Implications for idiopathic Parkinson's disease.

Gómez-Gálvez, Yolanda; Fuller, Heidi R; Synowsky, Silvia; Shirran, Sally L; Gates, Monte A

Gómez-Gálvez, Yolanda; Fuller, Heidi R; Synowsky, Silvia; Shirran, Sally L; Gates, Monte A.

Afiliación

Gómez-Gálvez Y; School of Pharmacy and Bioengineering, Keele University, Keele, UK.
Fuller HR; School of Medicine, Keele University, Keele, UK.
Synowsky S; School of Pharmacy and Bioengineering, Keele University, Keele, UK.
Shirran SL; Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK.
Gates MA; BSRC Mass Spectrometry and Proteomics Facility, University of St Andrews, Fife, UK.

J Neurosci Res ; 98(7): 1417-1432, 2020 07.

Article en En | MEDLINE | ID: mdl-32270889

Asunto(s)

Envejecimiento/metabolismo; Neuronas Dopaminérgicas/metabolismo; Proteína Ácida Fibrilar de la Glía/metabolismo; Enfermedad de Parkinson/metabolismo; Sustancia Negra/metabolismo; Animales; Astrocitos/metabolismo; Femenino; Masculino; Proteómica; Ratas; Ratas Sprague-Dawley

Palabras clave

RRID:AB_11145309; RRID:AB_2109791; RRID:AB_228307; RRID:AB_228341; RRID:AB_2336820; RRID:AB_2631098; RRID:AB_390204; RRID:MGI:5651135; RRID:SCR_001881; RRID:SCR_002798; RRID:SCR_003070; RRID:SCR_004946; RRID:SCR_005223; aging; dopaminergic neuron; glial fibrillary acidic protein; proteome; proteomics; substantia nigra

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Envejecimiento / Sustancia Negra / Neuronas Dopaminérgicas / Proteína Ácida Fibrilar de la Glía Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Neurosci Res Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google