Decreased slow-wave sleep and enlarged lateral ventricles in schizophrenia.
Neuropsychopharmacology
; 1(4): 265-71, 1988 Dec.
Article
en En
| MEDLINE
| ID: mdl-3251506
ABSTRACT
All-night electroencephalogram measures were evaluated against computed tomography scan measures, negative symptoms, and premorbid personality assessment in ten drug-free male schizophrenic patients. Computed tomography scan measures included ventricle brain ratio, cortical atrophy, and width of the third ventricle. Decreased stage-4 sleep was associated with enlarged VBR, poor premorbid functioning, and negative symptoms. Size of the VBR accounted for 58.5% of the variance in stage-4 sleep. Brain atrophy was associated with longer sleep latency but with less arousals once the patients were asleep. Rapid-eye-movement measures did not correlate significantly with any of the variables examined. Our data suggest that decreased slow-wave sleep and ventricle size are associated in schizophrenia.
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Bases de datos:
MEDLINE
Asunto principal:
Esquizofrenia
/
Psicología del Esquizofrénico
/
Sueño
/
Encéfalo
/
Ventrículos Cerebrales
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Neuropsychopharmacology
Asunto de la revista:
NEUROLOGIA
/
PSICOFARMACOLOGIA
Año:
1988
Tipo del documento:
Article