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Discovery of hydroxy pyrimidine Factor IXa inhibitors.
Jayne, Charles L; Andreani, Teresa; Chan, Tin-Yau; Chelliah, Mariappan V; Clasby, Martin C; Dwyer, Michael; Eagen, Keith A; Fried, Steve; Greenlee, William J; Guo, Zhuyan; Hawes, Brian; Hruza, Alan; Ingram, Richard; Keertikar, Kartik M; Neelamkavil, Santhosh; Reichert, Paul; Xia, Yan; Chackalamannil, Samuel.
Afiliación
  • Jayne CL; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA. Electronic address: Charles.Jayne@merck.com.
  • Andreani T; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Chan TY; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Chelliah MV; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Clasby MC; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Dwyer M; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Eagen KA; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Fried S; Department of Biology, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Greenlee WJ; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Guo Z; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Hawes B; Department of Biology, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Hruza A; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Ingram R; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Keertikar KM; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Neelamkavil S; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Reichert P; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Xia Y; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Chackalamannil S; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
Bioorg Med Chem Lett ; 30(15): 127279, 2020 08 01.
Article en En | MEDLINE | ID: mdl-32527459
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirimidinas / Factor IXa / Descubrimiento de Drogas / Inhibidores del Factor Xa Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirimidinas / Factor IXa / Descubrimiento de Drogas / Inhibidores del Factor Xa Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article