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Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.
Cox, Robert M; Sourimant, Julien; Toots, Mart; Yoon, Jeong-Joong; Ikegame, Satoshi; Govindarajan, Mugunthan; Watkinson, Ruth E; Thibault, Patricia; Makhsous, Negar; Lin, Michelle J; Marengo, Jose R; Sticher, Zachary; Kolykhalov, Alexander A; Natchus, Michael G; Greninger, Alexander L; Lee, Benhur; Plemper, Richard K.
Afiliación
  • Cox RM; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
  • Sourimant J; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
  • Toots M; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
  • Yoon JJ; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
  • Ikegame S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Govindarajan M; Emory Institute for Drug Development, Emory University, Atlanta, GA, USA.
  • Watkinson RE; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Thibault P; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Makhsous N; Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA, USA.
  • Lin MJ; Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA, USA.
  • Marengo JR; Emory Institute for Drug Development, Emory University, Atlanta, GA, USA.
  • Sticher Z; Emory Institute for Drug Development, Emory University, Atlanta, GA, USA.
  • Kolykhalov AA; Emory Institute for Drug Development, Emory University, Atlanta, GA, USA.
  • Natchus MG; Emory Institute for Drug Development, Emory University, Atlanta, GA, USA.
  • Greninger AL; Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA, USA.
  • Lee B; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Plemper RK; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA. rplemper@gsu.edu.
Nat Microbiol ; 5(10): 1232-1246, 2020 10.
Article en En | MEDLINE | ID: mdl-32661315
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Antivirales / ARN Polimerasas Dirigidas por ADN / Respirovirus / Inhibidores Enzimáticos Límite: Animals / Humans Idioma: En Revista: Nat Microbiol Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Antivirales / ARN Polimerasas Dirigidas por ADN / Respirovirus / Inhibidores Enzimáticos Límite: Animals / Humans Idioma: En Revista: Nat Microbiol Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos