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Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects.
Hakim-Eshed, Vicky; Boulos, Ayub; Cohen-Rosenzweig, Chen; Yu-Taeger, Libo; Ziv, Tamar; Kwon, Yong Tae; Riess, Olaf; Phuc Nguyen, Hoa Huu; Ziv, Noam E; Ciechanover, Aaron.
Afiliación
  • Hakim-Eshed V; The Rappaport Faculty of Medicine and Research Institute, 3109601 Haifa, Israel.
  • Boulos A; Network Biology Research Laboratories, Technion-Israel Institute of Technology, 3200003 Haifa, Israel.
  • Cohen-Rosenzweig C; The Rappaport Faculty of Medicine and Research Institute, 3109601 Haifa, Israel.
  • Yu-Taeger L; Network Biology Research Laboratories, Technion-Israel Institute of Technology, 3200003 Haifa, Israel.
  • Ziv T; The Rappaport Faculty of Medicine and Research Institute, 3109601 Haifa, Israel.
  • Kwon YT; The Technion Integrated Cancer Center (TICC), Technion-Israel Institute of Technology, 3109601 Haifa, Israel.
  • Riess O; Department of Human Genetics, Medical Faculty, Ruhr University Bochum, 44801 Bochum, Germany.
  • Phuc Nguyen HH; Smoler Proteomics Center, Faculty of Biology, Technion-Israel Institute of Technology, 3200003 Haifa, Israel.
  • Ziv NE; Department of Biomedical Sciences, Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul, South Korea.
  • Ciechanover A; Medical Genetics and Applied Genomics Medicine, Eberhard Karl University, 72074 Tuebingen, Germany.
Proc Natl Acad Sci U S A ; 117(31): 18661-18669, 2020 08 04.
Article en En | MEDLINE | ID: mdl-32675242
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Ubiquitinación / Proteína Huntingtina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article País de afiliación: Israel
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Ubiquitinación / Proteína Huntingtina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article País de afiliación: Israel