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Extracellular vesicles engineered with valency-controlled DNA nanostructures deliver CRISPR/Cas9 system for gene therapy.
Zhuang, Jialang; Tan, Jizhou; Wu, Chenglin; Zhang, Jie; Liu, Ting; Fan, Chunhai; Li, Jiaping; Zhang, Yuanqing.
Afiliación
  • Zhuang J; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, China.
  • Tan J; Department of Interventional Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P. R. China.
  • Wu C; Department of Interventional Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P. R. China.
  • Zhang J; Organ Transplantation Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P. R. China.
  • Liu T; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, China.
  • Fan C; Department of Interventional Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P. R. China.
  • Li J; School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Dongchuan Rd 800, Shanghai 200240, P. R. China.
  • Zhang Y; Department of Interventional Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P. R. China.
Nucleic Acids Res ; 48(16): 8870-8882, 2020 09 18.
Article en En | MEDLINE | ID: mdl-32810272
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Terapia Genética / Nanoestructuras / Aptámeros de Nucleótidos / Sistemas CRISPR-Cas / Vesículas Extracelulares / Neoplasias Hepáticas Límite: Animals / Female / Humans Idioma: En Revista: Nucleic Acids Res Año: 2020 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Terapia Genética / Nanoestructuras / Aptámeros de Nucleótidos / Sistemas CRISPR-Cas / Vesículas Extracelulares / Neoplasias Hepáticas Límite: Animals / Female / Humans Idioma: En Revista: Nucleic Acids Res Año: 2020 Tipo del documento: Article País de afiliación: China