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Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0.
Andrade, Sheila Siqueira; Faria, Alessandra Valéria de Sousa; Girão, Manoel João Batista C; Fuhler, Gwenny M; Peppelenbosch, Maikel P; Ferreira-Halder, Carmen V.
Afiliación
  • Andrade SS; PlateInnove Biotechnology, Piracicaba, SP 13414-018, Brazil.
  • Faria AVS; Department of Biochemistry and Tissue Biology, University of Campinas, UNICAMP, Campinas, SP 13083-862, Brazil.
  • Girão MJBC; Department of Gastroenterology and Hepatology Medical Center Rotterdam, NL-3000 CA Rotterdam, The Netherlands.
  • Fuhler GM; Department of Gynecology, Federal University of São Paulo, UNIFESP, São Paulo, SP 04024-002, Brazil.
  • Peppelenbosch MP; Department of Gastroenterology and Hepatology Medical Center Rotterdam, NL-3000 CA Rotterdam, The Netherlands.
  • Ferreira-Halder CV; Department of Gastroenterology and Hepatology Medical Center Rotterdam, NL-3000 CA Rotterdam, The Netherlands.
Int J Mol Sci ; 21(17)2020 Aug 23.
Article en En | MEDLINE | ID: mdl-32842455
The increasing discoveries regarding the biology and functions of platelets in the last decade undoubtedly show that these cells are one of the most biotechnological human cells. This review summarizes new advances in platelet biology, functions, and new concepts of biotech-educated platelets that connect advanced biomimetic science to platelet-based additive manufacturing for tissue regeneration. As highly responsive and secretory cells, platelets could be explored to develop solutions that alter injured microenvironments through platelet-based synthetic biomaterials with instructive extracellular cues for morphogenesis in tissue engineering beyond tissue regeneration 2.0.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cicatrización de Heridas / Plaquetas / Ingeniería de Tejidos Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Brasil

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cicatrización de Heridas / Plaquetas / Ingeniería de Tejidos Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Brasil