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Lung transplantation during the COVID-19 pandemic: Safely navigating the new "normal".
Halpern, Samantha E; Olaso, Danae G; Krischak, Madison K; Reynolds, John M; Haney, John C; Klapper, Jacob A; Hartwig, Matthew G.
Afiliación
  • Halpern SE; School of Medicine, Duke University, Durham, NC, USA.
  • Olaso DG; School of Medicine, Duke University, Durham, NC, USA.
  • Krischak MK; School of Medicine, Duke University, Durham, NC, USA.
  • Reynolds JM; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
  • Haney JC; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC, USA.
  • Klapper JA; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC, USA.
  • Hartwig MG; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC, USA.
Am J Transplant ; 20(11): 3094-3105, 2020 11.
Article en En | MEDLINE | ID: mdl-32894641
In the United States, an overall national decline in organ transplants has accompanied the substantial burden of COVID-19. Amidst significant regional variations in COVID-19, lung transplantation (LTx) remains a critical life-saving operation. Our LTx practice during the early pandemic may provide a blueprint for managing LTx in an era of continued community prevalence. Patients who underwent LTx at our institution between March 1 and May 20, 2020 were included. Recipient, operative, and donor characteristics were compared to those from our program in 2019, and COVID-19 testing practices were evaluated for March, April, and May to understand how our practice adapted to the pandemic. Our program performed 36 LTx, 33% more than the same period in 2019. Recipient, operative, and donor characteristics during COVID-19 were similar to those in 2019. By April 1, all donors and recipients underwent pretransplant COVID-19 testing, all returning negative results. To date, no recipients have developed posttransplant COVID-19. At our institution, pretransplant COVID-19 testing, use of local donor lungs, and avoidance of donors from areas of increased community penetration supported a safe and effective LTx practice during the early COVID-19 pandemic. Continued follow-up is required to ensure the long-term safety of these newly transplanted patients.
Asunto(s)

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Donantes de Tejidos / Trasplante de Pulmón / Pandemias / Receptores de Trasplantes / SARS-CoV-2 / COVID-19 Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Donantes de Tejidos / Trasplante de Pulmón / Pandemias / Receptores de Trasplantes / SARS-CoV-2 / COVID-19 Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos