ST09, A Novel Curcumin Derivative, Blocks Cell Migration by Inhibiting Matrix Metalloproteases in Breast Cancer Cells and Inhibits Tumor Progression in EAC Mouse Tumor Models.

Nirgude, Snehal; Mahadeva, Raghunandan; Koroth, Jinsha; Kumar, Sujeet; Kumar, Kothanahally S Sharath; Gopalakrishnan, Vidya; S Karki, Subhas S; Choudhary, Bibha

Nirgude, Snehal; Mahadeva, Raghunandan; Koroth, Jinsha; Kumar, Sujeet; Kumar, Kothanahally S Sharath; Gopalakrishnan, Vidya; S Karki, Subhas S; Choudhary, Bibha.

Afiliación

Nirgude S; Institute of Bioinformatics and Applied Biotechnology, Electronic City Phase 1, Bangalore 560100, India.
Mahadeva R; Manipal Academy of Higher Education, Manipal 576104, India.
Koroth J; Institute of Bioinformatics and Applied Biotechnology, Electronic City Phase 1, Bangalore 560100, India.
Kumar S; Institute of Bioinformatics and Applied Biotechnology, Electronic City Phase 1, Bangalore 560100, India.
Kumar KSS; Department of Pharmaceutical Chemistry, KLE College of Pharmacy, Rajajinagar, (A Constituent Unit of KLE Academy of Higher Education & Research, Belagavi), KN, Bangalore 5600, India.
Gopalakrishnan V; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru-570006, India.
S Karki SS; St. Joseph's College, Irinjalakuda, Kerala 680661, India.
Choudhary B; Department of Pharmaceutical Chemistry, KLE College of Pharmacy, Rajajinagar, (A Constituent Unit of KLE Academy of Higher Education & Research, Belagavi), KN, Bangalore 5600, India.

Molecules ; 25(19)2020 Sep 30.

Article en En | MEDLINE | ID: mdl-33008036

Asunto(s)

Neoplasias de la Mama/enzimología; Neoplasias de la Mama/patología; Movimiento Celular/efectos de los fármacos; Curcumina/análogos & derivados; Curcumina/farmacología; Progresión de la Enfermedad; Neoplasias Mamarias Animales/patología; Aloinjertos/efectos de los fármacos; Animales; Puntos de Control del Ciclo Celular/efectos de los fármacos; Muerte Celular/efectos de los fármacos; Línea Celular Tumoral; Curcumina/química; Modelos Animales de Enfermedad; Femenino; Humanos; Concentración 50 Inhibidora; Metaloproteinasas de la Matriz/metabolismo; Potencial de la Membrana Mitocondrial/efectos de los fármacos; Ratones; Pruebas de Toxicidad

Palabras clave

EAC mouse tumor model; MCF7; MDA-MB-231; apoptosis; immunity boosting cancer therapeutics; migrastatic

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Neoplasias Mamarias Animales / Movimiento Celular / Progresión de la Enfermedad / Curcumina Límite: Animals / Female / Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: India

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