Discovery, Pharmacological Characterisation and NMR Structure of the Novel µ-Conotoxin SxIIIC, a Potent and Irreversible Na<sub>V</sub> Channel Inhibitor.

McMahon, Kirsten L; Tran, Hue N T; Deuis, Jennifer R; Lewis, Richard J; Vetter, Irina; Schroeder, Christina I

Discovery, Pharmacological Characterisation and NMR Structure of the Novel µ-Conotoxin SxIIIC, a Potent and Irreversible Na_V Channel Inhibitor.

McMahon, Kirsten L; Tran, Hue N T; Deuis, Jennifer R; Lewis, Richard J; Vetter, Irina; Schroeder, Christina I.

Afiliación

McMahon KL; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Tran HNT; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Deuis JR; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Lewis RJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Vetter I; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Schroeder CI; The School of Pharmacy, The University of Queensland, Woolloongabba, QLD 4102, Australia.

Biomedicines ; 8(10)2020 Oct 02.

Article en En | MEDLINE | ID: mdl-33023152

Palabras clave

NMR; NaV channels; chronic pain; pore blocker; whole-cell patch-clamp electrophysiology; µ-conotoxin

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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Biomedicines Año: 2020 Tipo del documento: Article País de afiliación: Australia

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