Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10.

Feng, Han; Tian, Huabin; Wang, Yong; Zhang, Qixiang; Lin, Ni; Liu, Songqing; Yu, Yang; Deng, Hongyu; Gao, Pu

Feng, Han; Tian, Huabin; Wang, Yong; Zhang, Qixiang; Lin, Ni; Liu, Songqing; Yu, Yang; Deng, Hongyu; Gao, Pu.

Afiliación

Feng H; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Tian H; CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Wang Y; CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Zhang Q; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Lin N; CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Liu S; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Yu Y; CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Deng H; CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Gao P; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

Proc Natl Acad Sci U S A ; 117(43): 26719-26727, 2020 10 27.

Article en En | MEDLINE | ID: mdl-33033226

Asunto(s)

Transporte de ARN/fisiología; ARN Mensajero/metabolismo; Transactivadores/metabolismo; Animales; Células HEK293; Interacciones Huésped-Patógeno; Humanos; Ratones; Proteínas Asociadas a Matriz Nuclear/química; Proteínas Asociadas a Matriz Nuclear/metabolismo; Proteínas de Complejo Poro Nuclear/química; Proteínas de Complejo Poro Nuclear/metabolismo; Proteínas de Transporte Nucleocitoplasmático/química; Proteínas de Transporte Nucleocitoplasmático/metabolismo; ARN Mensajero/química; Células Sf9; Transactivadores/química

Palabras clave

Nup98; ORF10; RNA nuclear export; Rae1; herpesvirus

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: ARN Mensajero / Transactivadores / Transporte de ARN Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article País de afiliación: China

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