A mathematical approach to severe hyponatremia and hypernatremia in renal replacement therapies.
Semin Dial
; 34(1): 42-50, 2021 01.
Article
en En
| MEDLINE
| ID: mdl-33063373
ABSTRACT
Severe dysnatremias are perplexing problems in patients undergoing renal replacement therapy on a chronic or acute basis. The ability to manipulate sodium concentration in the dialysate or replacement solutions is limited. Compounding dialysate or replacement fluids to alter sodium concentration could result in errors. Rapid correction of hyponatremia or hypernatremia due to equilibrium with dialysate or replacement solutions could lead to osmotic demyelination syndrome or cerebral edema respectively. Continuous renal replacement therapy is the preferred dialysis modality in patients with severe dysnatremias. In this article, we present simple formulas to determine the rate of hypotonic or hypertonic solutions needed to mitigate rapid correction of dysnatremias. These formulas can be used readily by the clinician at bedside.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Hipernatremia
/
Hiponatremia
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Semin Dial
Asunto de la revista:
NEFROLOGIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Estados Unidos