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Incidence, clinical, risk factors and outcomes of Guillain-Barré in Covid-19.
Fragiel, Marcos; Miró, Òscar; Llorens, Pere; Jiménez, Sònia; Piñera, Pascual; Burillo, Guillermo; Martín, Alfonso; Martín-Sánchez, Francisco J; García-Lamberechts, Eric J; Jacob, Javier; Alquézar-Arbé, Aitor; Juárez, Ricardo; Jiménez, Blas; Del Rio, Rigoberto; Mateo Roca, Miriam; García, Arturo H; López Laguna, Nieves; Lopez Diez, María P; Pedraza García, Jorge; Fernández de Simón Almela, Amparo; Lopez Diaz, Juan J; Eiroa Hernández, Patricia; Ruiz de Lobera, Noemí; Porta-Etessam, Jesús; Fernández Pérez, Cristina; Calvo, Elpidio; González Del Castillo, Juan.
Afiliación
  • Fragiel M; Emergency Department, San Carlos Clinical Hospital, Instituto de Investigación Sanitaria San Carlos (San Carlos Health Research Institute), Complutense University, Madrid, Spain.
  • Miró Ò; Emergency Department, Clinical Hospital, Instituto de Investigaciones Biomédicas August Pi i Sunyer (August Pi i Sunyer Institute for Biomedical Research), University of Barcelona, Barcelona, Spain.
  • Llorens P; Emergency Department, Alicante General Hospital, Miguel Hernández University, Alicante, Spain.
  • Jiménez S; Emergency Department, Clinical Hospital, Instituto de Investigaciones Biomédicas August Pi i Sunyer (August Pi i Sunyer Institute for Biomedical Research), University of Barcelona, Barcelona, Spain.
  • Piñera P; Emergency Department, Reina Sofía Hospital, Murcia, Spain.
  • Burillo G; Emergency Department, University Hospital of the Canary Islands, Tenerife, Spain.
  • Martín A; Emergency Department, Severo Ochoa Hospital, Leganés, Madrid, Spain.
  • Martín-Sánchez FJ; Emergency Department, San Carlos Clinical Hospital, Instituto de Investigación Sanitaria San Carlos (San Carlos Health Research Institute), Complutense University, Madrid, Spain.
  • García-Lamberechts EJ; Emergency Department, San Carlos Clinical Hospital, Instituto de Investigación Sanitaria San Carlos (San Carlos Health Research Institute), Complutense University, Madrid, Spain.
  • Jacob J; Emergency Department, Bellvitge University Hospital, Barcelona, Spain.
  • Alquézar-Arbé A; Emergency Department, Hospital of the Holy Cross and Saint Paul, Barcelona, Spain.
  • Juárez R; Emergency Department, Our Lady Prado Hospital of Talavera de la Reina, Toledo, Spain.
  • Jiménez B; Emergency Department, Vinalopó de Elche University Hospital, Alicante, Spain.
  • Del Rio R; Emergency Department, University Hospital of Torrevieja de Alicante, Alicante, Spain.
  • Mateo Roca M; Emergency Department, Hospital of the Holy Cross and Saint Paul, Barcelona, Spain.
  • García AH; Emergency Department, Sacred Family Clinic, Barcelona, Spain.
  • López Laguna N; Emergency Department, Navarra University Clinic of Madrid, Madrid, Spain.
  • Lopez Diez MP; Emergency Department, Burgos University Hospital, Burgos, Spain.
  • Pedraza García J; Emergency Department, Los Pedroches Valley Regional Hospital, Córdoba, Spain.
  • Fernández de Simón Almela A; Emergency Department, Virgin of the Rocio Hospital of Seville, Sevilla, Spain.
  • Lopez Diaz JJ; Emergency Department, Lucus Augusti Lugo University Hospital, Lugo, Spain.
  • Eiroa Hernández P; Emergency Department, Canary Islands University Hospital, Tenerife, Spain.
  • Ruiz de Lobera N; Emergency Department, San Pedro Hospital of Logroño, Logroño, Spain.
  • Porta-Etessam J; Neurology Department, San Carlos Clinical Hospital, Madrid, Spain.
  • Fernández Pérez C; Preventive Medicina Department, Santiago de Compostela Hospital Complex, La Coruña, Spain.
  • Calvo E; Internal Medicine Department, San Carlos Clinical Hospital, Instituto de Investigación Sanitaria San Carlos (San Carlos Health Research Institute), Complutense University, Madrid, Spain.
  • González Del Castillo J; Emergency Department, San Carlos Clinical Hospital, Instituto de Investigación Sanitaria San Carlos (San Carlos Health Research Institute), Complutense University, Madrid, Spain.
Ann Neurol ; 89(3): 598-603, 2021 03.
Article en En | MEDLINE | ID: mdl-33295021
We diagnosed 11 Guillain-Barré syndrome (GBS) cases among 71,904 COVID patients attended at 61 Spanish emergency departments (EDs) during the 2-month pandemic peak. The relative frequency of GBS among ED patients was higher in COVID (0.15‰) than non-COVID (0.02‰) patients (odds ratio [OR] = 6.30, 95% confidence interval [CI] = 3.18-12.5), as was the standardized incidence (9.44 and 0.69 cases/100,000 inhabitant-years, respectively, OR = 13.5, 95% CI = 9.87-18.4). Regarding clinical characteristics, olfactory-gustatory disorders were more frequent in COVID-GBS than non-COVID-GBS (OR = 27.59, 95% CI = 1.296-587) and COVID-non-GBS (OR = 7.875, 95% CI = 1.587-39.09) patients. Although COVID-GBS patients were more frequently admitted to intensive care, mortality was not increased versus control groups. Our results suggest SARS-CoV-2 could be another viral infection causing GBS. ANN NEUROL 2021;89:598-603.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Trastornos del Gusto / Mortalidad Hospitalaria / Síndrome de Guillain-Barré / COVID-19 / Unidades de Cuidados Intensivos / Tiempo de Internación / Trastornos del Olfato Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Ann Neurol Año: 2021 Tipo del documento: Article País de afiliación: España
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Trastornos del Gusto / Mortalidad Hospitalaria / Síndrome de Guillain-Barré / COVID-19 / Unidades de Cuidados Intensivos / Tiempo de Internación / Trastornos del Olfato Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Ann Neurol Año: 2021 Tipo del documento: Article País de afiliación: España