Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic Malignancies.

Gummadi, Venkateshwar Rao; Boruah, Anima; Ainan, Bharathi Raja; Vare, Brahma Reddy; Manda, Srinivas; Gondle, Hari Prakash; Kumar, Shiva Nagendra; Mukherjee, Subhendu; Gore, Suraj T; Krishnamurthy, Narasimha Rao; Marappan, Sivapriya; Nayak, Shilpa S; Nellore, Kavitha; Balasubramanian, Wesley Roy; Bhumireddy, Archana; Giri, Sanjeev; Gopinath, Sreevalsam; Samiulla, Dodheri S; Daginakatte, Girish; Basavaraju, Aravind; Chelur, Shekar; Eswarappa, Rajesh; Belliappa, Charamanna; Subramanya, Hosahalli S; Booher, Robert N; Ramachandra, Murali; Samajdar, Susanta

Gummadi, Venkateshwar Rao; Boruah, Anima; Ainan, Bharathi Raja; Vare, Brahma Reddy; Manda, Srinivas; Gondle, Hari Prakash; Kumar, Shiva Nagendra; Mukherjee, Subhendu; Gore, Suraj T; Krishnamurthy, Narasimha Rao; Marappan, Sivapriya; Nayak, Shilpa S; Nellore, Kavitha; Balasubramanian, Wesley Roy; Bhumireddy, Archana; Giri, Sanjeev; Gopinath, Sreevalsam; Samiulla, Dodheri S; Daginakatte, Girish; Basavaraju, Aravind; Chelur, Shekar; Eswarappa, Rajesh; Belliappa, Charamanna; Subramanya, Hosahalli S; Booher, Robert N; Ramachandra, Murali; Samajdar, Susanta.

Afiliación

Gummadi VR; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Boruah A; Aurigene Discovery Technologies Ltd., Bollaram Road, Miyapur, Hyderabad 500 049, India.
Ainan BR; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Vare BR; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Manda S; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Gondle HP; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Kumar SN; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Mukherjee S; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Gore ST; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Krishnamurthy NR; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Marappan S; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Nayak SS; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Nellore K; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Balasubramanian WR; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Bhumireddy A; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Giri S; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Gopinath S; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Samiulla DS; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Daginakatte G; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Basavaraju A; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Chelur S; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Eswarappa R; Aurigene Discovery Technologies Ltd., Bollaram Road, Miyapur, Hyderabad 500 049, India.
Belliappa C; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Subramanya HS; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Booher RN; Curis Inc., 4 Maguire Road, Lexington, Massachusetts 02421, United States.
Ramachandra M; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.
Samajdar S; Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.

ACS Med Chem Lett ; 11(12): 2374-2381, 2020 Dec 10.

Article en En | MEDLINE | ID: mdl-33335659

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: ACS Med Chem Lett Año: 2020 Tipo del documento: Article País de afiliación: India