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Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma.
Robert, Caroline; Hwu, Wen-Jen; Hamid, Omid; Ribas, Antoni; Weber, Jeffrey S; Daud, Adil I; Hodi, F Stephen; Wolchok, Jedd D; Mitchell, Tara C; Hersey, Peter; Dronca, Roxana; Joseph, Richard W; Boutros, Celine; Min, Le; Long, Georgina V; Schachter, Jacob; Puzanov, Igor; Dummer, Reinhard; Lin, Jianxin; Ibrahim, Nageatte; Diede, Scott J; Carlino, Matteo S; Joshua, Anthony M.
Afiliación
  • Robert C; Department of Oncology, Service of Dermatology, Institut de Cancérologie Gustave Roussy, 114 Rue Edouard Vaillant, Gustave Roussy, Villejuif, 94805, France; Paris-Saclay University, CNRS UMR 3348, Orsay, France. Electronic address: caroline.robert@gustaveroussy.fr.
  • Hwu WJ; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Electronic address: hwu.wenjen@gmail.com.
  • Hamid O; Department of Hematology/Oncology, The Angeles Clinic and Research Institute, a Cedars-Sinai Affiliate, 11800 Wilshire Blvd Suite 300, Los Angeles, CA, 90025, USA. Electronic address: ohamid@theangelesclinic.org.
  • Ribas A; Department of Medicine and the Jonsson Comprehensive Cancer Center, University of California, Los Angeles (UCLA), 11-934 Factor bldg., Los Angeles, CA, 90095, USA. Electronic address: aribas@mednet.ucla.edu.
  • Weber JS; Department of Medicine, Laura and Isaac Perlmutter Cancer Center at NYU Langone Health, 522 First Avenue, 1310 Smilow Building, New York, NY, 10016, USA. Electronic address: Jeffrey.Weber@nyulangone.org.
  • Daud AI; Department of Medicine, University of California San Francisco, 1600 Divisadero St, San Francisco, CA, 94158, USA. Electronic address: adaud@medicine.ucsf.edu.
  • Hodi FS; Melanoma Center and Center for Immuno-Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA, 02215, USA. Electronic address: Stephen_Hodi@dfci.harvard.edu.
  • Wolchok JD; Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA. Electronic address: wolchokj@mskcc.org.
  • Mitchell TC; Division of Hematology and Oncology, Abramson Cancer Center, University of Pennsylvania, 3400 Civic Center Blvd South Pavilion, Flr 10, Philadelphia, PA, 19104, USA. Electronic address: tara.mitchell@uphs.upenn.edu.
  • Hersey P; Department of Medicine, The University of Sydney, Camperdown, NSW, 2006, Australia; Centenary Institute, Misendon Rd, Bldg 93, Camperdown, NSW, 2050, Australia; Melanoma Institute Australia, The University of Sydney, 40 Rocklands Rd, Wollstonecraft, NSW, 2065, Australia. Electronic address: peter.he
  • Dronca R; Department of Hematology/Oncology, Mayo Clinic, 200 1st St. SW, Rochester, MN, 55905, USA. Electronic address: Dronca.Roxana@mayo.edu.
  • Joseph RW; Division of Cancer Medicine, Mayo Clinic Cancer Center-Florida, 4500 San Pablo Rd, Jacksonville, FL, 32224, USA. Electronic address: joseph.richard@mayo.edu.
  • Boutros C; Department of Oncology, Service of Dermatology, Institut de Cancérologie Gustave Roussy, 114 Rue Edouard Vaillant, Gustave Roussy, Villejuif, 94805, France. Electronic address: celine.boutros@gustaveroussy.fr.
  • Min L; Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA, 02115, USA. Electronic address: lmin@bwh.harvard.edu.
  • Long GV; Melanoma Institute Australia, The University of Sydney, 40 Rocklands Rd, Wollstonecraft, NSW, 2065, Australia; Royal North Shore Hospital, Reserve Road, St Leonards, NSW, 2065, Australia; Mater Hospital, Wollstonecraft, NSW, 2065, Australia; Faculty of Medicine and Health, The University of Sydney,
  • Schachter J; Division of Oncology, Level 2 Cancer Center, Sheba Medical Center, Tel HaShomer Hospital, Emek HaEla Street 1, Tel HaShomer, Ramat Gan, 52621, Israel. Electronic address: jacob.schachter@sheba.health.gov.il.
  • Puzanov I; Melanoma Section Department of Medicine, Roswell Park Comprehensive Cancer Center, 915 CSC Building, Elm & Carlton Streets, Buffalo, NY, 14263, USA. Electronic address: Igor.Puzanov@RoswellPark.org.
  • Dummer R; Department of Dermatology, University Hospital Zürich, University of Zurich, Rämistrasse 100, Zürich, 8091, Switzerland. Electronic address: reinhard.Dummer@usz.ch.
  • Lin J; Department of Clinical Oncology, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033, USA. Electronic address: jianxin_lin@merck.com.
  • Ibrahim N; Department of Clinical Oncology, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033, USA. Electronic address: nageatte.ibrahim@merck.com.
  • Diede SJ; Department of Clinical Oncology, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033, USA. Electronic address: scott.diede@merck.com.
  • Carlino MS; Department of Medicine, The University of Sydney, Camperdown, NSW, 2006, Australia; Melanoma Institute Australia, The University of Sydney, 40 Rocklands Rd, Wollstonecraft, NSW, 2065, Australia; Department of Medical Oncology, The Crown Princess Mary Cancer Centre, Westmead Hospital, 12 Moris Road,
  • Joshua AM; Melanoma Institute Australia, The University of Sydney, 40 Rocklands Rd, Wollstonecraft, NSW, 2065, Australia; Department of Medical Oncology, Princess Margaret Cancer Centre, University Health Network, 610 University Ave, Toronto, ON, M5G2C1, Canada; The Kinghorn Cancer Centre at St Vincent's Hospi
Eur J Cancer ; 144: 182-191, 2021 02.
Article en En | MEDLINE | ID: mdl-33360855
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ensayos Clínicos como Asunto / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Anticuerpos Monoclonales Humanizados / Antineoplásicos Inmunológicos / Melanoma Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Systematic_reviews Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Cancer Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ensayos Clínicos como Asunto / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Anticuerpos Monoclonales Humanizados / Antineoplásicos Inmunológicos / Melanoma Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Systematic_reviews Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Cancer Año: 2021 Tipo del documento: Article